Paper Details

  1. Home
  2. Paper Details

Comparison of preoperative and postoperative radiation therapy for patients with carcinoma of the head and neck. Interim report.

Author: DavisL W, GelberR D, KramerS, LowryL D, MarcialV A, SnowJ B

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This interim report on 320 patients with squamous cell carcinoma of the head and neck found that surgery followed by postoperative radiation therapy was significantly better for local control in patients with supraglottic larynx cancer. There were no statistically significant treatment differences in local control or survival for other sites, including oral cavity, oropharynx, and hypopharynx.
Paper Details　
Original Abstract of the Article :
Three hundred and fifty-four patients with squamous cell carcinoma of the oral cavity, oropharynx, supraglottic larynx, hypopharynx or maxillary sinus have been randomized for preoperative radiation therapy and surgery versus surgery and postoperative radiation therapy plus, in the case of patients ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.3109/00016488109138548

データ提供：米国国立医学図書館（NLM）

A Battleground of Choice: Preoperative vs. Postoperative Radiation Therapy

The world of [head and neck cancer treatment] is a complex and often demanding battlefield. This research explores the effectiveness of two different approaches to treating squamous cell carcinoma of the head and neck: preoperative radiation therapy and postoperative radiation therapy. The authors analyze the outcomes of 320 patients in an interim report, comparing the two strategies in a quest for the most effective weapon against this formidable foe.

The Quest for the Winning Strategy: Preoperative vs. Postoperative

The study found that postoperative radiation therapy was more effective in achieving local-regional control for patients with supraglottic larynx cancer. This is like discovering a more effective sword in the desert, offering a stronger shield against the enemy. However, no statistically significant differences were found in local-regional control or survival for other sites. This is like encountering different terrains in the desert – some areas require a specific approach, while others demand a more versatile strategy.

Navigating the Battlefield of Head and Neck Cancer

This research provides valuable insights into the complexities of head and neck cancer treatment. The authors emphasize the importance of considering individual patient characteristics and the specific site of the tumor when choosing the most appropriate treatment strategy. This is like adapting your tactics to the terrain, ensuring a more effective and successful campaign against the enemy.

Dr. Camel's Conclusion

This research highlights the ongoing battle against head and neck cancer, emphasizing the importance of exploring different strategies and tailoring treatment plans to individual patient needs. The study reminds us that the desert of medical research is constantly evolving, offering new weapons and insights in the fight against disease.

Date :
  1. Date Completed 1981-10-29
  2. Date Revised 2019-07-16
Further Info :

Pubmed ID

7270130

DOI: Digital Object Identifier

10.3109/00016488109138548

Related Literature

Article Analysis
・Effective treatment of radiation therapy
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.