Initial and long-term effects of metoprolol and timolol on the intraocular pressure. A comparison in healthy subjects.

Author: AlmA, TörnquistP, WickströmC P

Paper Details 
Original Abstract of the Article :
The effect of 3% metoprolol and 0.5% timolol eye drops on the intraocular pressure (IOP) was compared in healthy subjects. The effect of a single dose was determined up to 48 h after administration of the drug before and after 2 weeks' treatment twice daily with the test drug. The study was performe...See full text at original site
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引用元:
https://doi.org/10.1111/j.1755-3768.1981.tb08336.x

データ提供:米国国立医学図書館(NLM)

Metoprolol vs. Timolol: A Head-to-Head Comparison in Intraocular Pressure Control

The [intraocular pressure (IOP)] landscape is a delicate one, with researchers constantly seeking ways to effectively manage this crucial aspect of eye health. This study, like a camel carefully navigating a narrow desert path, compares the effects of two commonly used [beta-blockers], [metoprolol] and [timolol], on IOP in [healthy subjects]. The study, a [randomized, double-masked cross-over] design, provides valuable insights into the comparative efficacy of these medications. Researchers found that both drugs effectively reduced IOP, but timolol demonstrated a longer-lasting effect compared to metoprolol.

Timolol: A More Sustained Effect in IOP Reduction

The study revealed that while both drugs lowered IOP, timolol maintained its effect for at least 48 hours, while metoprolol's effect lasted for 36 hours. This difference, like a shimmering mirage, suggests that timolol may be a more suitable option for patients seeking sustained IOP control.

Keeping Your Eyes Healthy: Choosing the Right Medication

Understanding the duration of action of different IOP-lowering medications is essential for optimal eye health. This study underscores the importance of consulting a healthcare professional to determine the most appropriate treatment based on individual needs and risk factors. It's wise to choose a medication that effectively controls IOP and offers a sustained effect.

Dr.Camel's Conclusion

This study provides valuable insights into the comparative efficacy of metoprolol and timolol in reducing intraocular pressure. While both drugs were effective, timolol demonstrated a longer-lasting effect, suggesting that it may be a more suitable option for patients seeking sustained IOP control. Choosing the right IOP-lowering medication is essential for maintaining eye health and preventing vision loss.

Date :
  1. Date Completed 1982-02-12
  2. Date Revised 2019-08-21
Further Info :

Pubmed ID

7315207

DOI: Digital Object Identifier

10.1111/j.1755-3768.1981.tb08336.x

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