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Treatment of endogenous anxiety with phobic, hysterical, and hypochondriacal symptoms.

Author: BallengerJ, JacobsenG, SheehanD V

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study of 57 patients with endogenous anxiety found that both imipramine hydrochloride and pheneizine sulfate were significantly more effective than placebo in reducing anxiety symptoms. Pheneizine tended to be more effective than imipramine, particularly in improving work and social function.
Paper Details　
Original Abstract of the Article :
Endogenous anxiety (anxiety hysteria, agoraphobia with panic attacks) is characterized by sudden, spontaneous panic attacks accompanied by multiple autonomic symptoms, overwhelming fear, a flight response, and polyphobic behavior. Psychotherapy, behavior therapy, and tranquillizers have been of limi...See full text at original site
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引用元：
https://doi.org/10.1001/archpsyc.1980.01780140053006

データ提供：米国国立医学図書館（NLM）

Treating Endogenous Anxiety with Medications and Therapy

Anxiety disorders are prevalent mental health conditions that can significantly impact quality of life. This study investigates the effectiveness of imipramine hydrochloride, phenelzine sulfate, and placebo in treating endogenous anxiety, a specific type of anxiety characterized by sudden panic attacks and phobic behavior. The authors conducted a double-blind, placebo-controlled study involving 57 patients with severe, long-standing anxiety. Patients received medication and participated in supportive group therapy over a three-month period.

Finding Relief for Endogenous Anxiety

The study found that both imipramine and phenelzine were significantly more effective than placebo in reducing anxiety symptoms and improving functional capacity. Phenelzine demonstrated a slightly greater improvement compared to imipramine in certain areas. This research provides evidence for the potential benefit of medications, in conjunction with therapy, in addressing the challenges of endogenous anxiety.

Navigating the Sandstorms of Anxiety

This study highlights the complexity of anxiety disorders and the need for a multi-faceted approach to treatment. It underscores the importance of addressing both the psychological and biological aspects of anxiety, suggesting that a combination of medication and therapy can be a valuable tool in managing this challenging condition. It's like navigating a sandstorm, where a combination of skills and resources is needed to find clear skies and a path forward.

Dr.Camel's Conclusion

This study sheds light on the effectiveness of imipramine and phenelzine in treating endogenous anxiety, emphasizing the importance of a combined approach involving medication and therapy. The results offer hope for those struggling with this specific type of anxiety, reminding us that even in the desert of mental health challenges, there can be pathways towards relief and recovery.

Date :
  1. Date Completed 1980-03-24
  2. Date Revised 2019-07-17
Further Info :

Pubmed ID

7352840

DOI: Digital Object Identifier

10.1001/archpsyc.1980.01780140053006

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Languages

English

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