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Chronic administration of cannabidiol to healthy volunteers and epileptic patients.

Author: CarliniE A, CunhaJ M, GagliardiR, LanderN, MechoulamR, PereiraA E, PimentelC, RamosO L, SanvitoW L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Cannabidiol was effective in treating secondary generalized epilepsy with temporal focus. 4 out of 8 CBD subjects remained almost free of convulsive crises throughout the experiment. No signs of toxicity or serious side effects were detected.
Paper Details　
Original Abstract of the Article :
In phase 1 of the study, 3 mg/kg daily of cannabidiol (CBD) was given for 30 days to 8 health human volunteers. Another 8 volunteers received the same number of identical capsules containing glucose as placebo in a double-blind setting. Neurological and physical examinations, blood and urine analysi...See full text at original site
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引用元：
https://doi.org/10.1159/000137430

データ提供：米国国立医学図書館（NLM）

Cannabidiol: Exploring its Potential as an Antiepileptic Agent

Epilepsy, a neurological disorder characterized by recurrent seizures, often proves difficult to manage. Cannabidiol (CBD), a non-psychoactive component of cannabis, has shown potential as an antiepileptic agent. This research investigates the safety and efficacy of CBD in both healthy volunteers and patients with epilepsy. The authors conducted a two-phase study, evaluating the effects of CBD on neurological function, blood and urine parameters, and seizure frequency. This study provides valuable insights into CBD's potential therapeutic role in epilepsy management.

Cannabidiol: Potential Antiepileptic Effects and Tolerability

This study demonstrates that CBD is well-tolerated by both healthy volunteers and patients with epilepsy. The authors observed a significant reduction in seizure frequency in some patients, suggesting that CBD could offer a potential treatment option for epilepsy. However, further research is needed to confirm these findings and establish optimal dosing strategies.

Navigating the Desert of Epilepsy: Exploring Cannabidiol's Potential

Epilepsy, like a relentless desert storm, can disrupt the tranquility of the brain. CBD, like a calm oasis, offers potential relief from the disruptive forces of seizures. This research delves into the potential benefits of CBD, providing valuable insights into its potential role in epilepsy management.

Dr. Camel's Conclusion

This research highlights the potential of CBD as a therapeutic agent for epilepsy. While further research is needed to optimize its use, the study offers promising evidence for its safety and potential efficacy. The search for effective and safe treatments for epilepsy continues, and this research contributes valuable insights to this ongoing effort.

Date :
  1. Date Completed 1980-11-20
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

7413719

DOI: Digital Object Identifier

10.1159/000137430

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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