Paper Details 
Original Abstract of the Article :
1. Meclofenamate caused a dose-dependent increase in renovascular resistance in conscious rabbits. 2. This effect was greatest in inner cortical zones at the highest dose (6 mg/kg) but at the lowest dose (0.75 mg/kg) vascular resistance in the outer cortex was preferentially increased. 3. In contras...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/j.1440-1681.1980.tb00105.x

データ提供:米国国立医学図書館(NLM)

The Role of Prostaglandins in Renal and Peripheral Vascular Regulation

This research delves into the realm of [physiology] and investigates the effects of [meclofenamate] on [renal and peripheral vascular beds] in [conscious rabbits]. The study uses a [pharmacological] approach to examine the impact of meclofenamate on vascular resistance in various organs. The authors discovered that [meclofenamate caused a dose-dependent increase in renovascular resistance, preferentially affecting the outer cortical zones at lower doses and the inner cortical zones at higher doses]. The study also reveals that meclofenamate [increased cerebral perfusion and the proportion of cardiac output received by the testis], suggesting its potential effects on specific vascular beds.

Exploring the Complexities of Vascular Regulation

This study provides valuable insights into the intricate mechanisms of vascular regulation, highlighting the role of prostaglandins in modulating blood flow in various organs. The findings suggest that meclofenamate may have specific effects on different vascular beds, influencing blood flow distribution within the body.

Understanding Vascular Health

Just as a camel's circulatory system adapts to the harsh desert environment, our vascular system plays a vital role in maintaining our health. This research, like a detailed map of a desert landscape, offers insights into the intricate mechanisms of vascular regulation, guiding us towards a better understanding of our bodies.

Dr.Camel's Conclusion

Imagine a vast desert landscape, where water sources are scarce, and blood flow is crucial for survival. This research, like a skilled desert explorer, unveils the intricate workings of the vascular system, providing valuable insights into the role of prostaglandins in regulating blood flow and maintaining health.
Date :
  1. Date Completed 1981-03-17
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

7449196

DOI: Digital Object Identifier

10.1111/j.1440-1681.1980.tb00105.x

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SNS
PICO Info
in preparation
Languages

English

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