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Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group.
Author: BellN H, BröllJ, DequekerJ, DownsR W, FavusM, LibermanU A, MinneH W, QuanH, Rodriguez-PortalesJ, WeissS R
Original Abstract of the Article :
BACKGROUND: Postmenopausal osteoporosis is a serious health problem, and additional treatments are needed. METHODS: We studied the effects of oral alendronate, an aminobisphosphonate, on bone mineral density and the incidence of fractures and height loss in 994 women with postmenopausal osteoporosi...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1056/NEJM199511303332201
データ提供:米国国立医学図書館(NLM)
Alendronate: A Fortress in the Desert of Osteoporosis
Osteoporosis, like a desert landscape eroded by wind and time, can weaken bones, making them susceptible to fractures. The field of bone health is constantly exploring ways to strengthen bones and prevent fractures, and this study, like a caravan seeking a safe haven, examines the effects of alendronate, an aminobisphosphonate, on bone mineral density and fracture incidence in postmenopausal women with osteoporosis.
The researchers conducted a large-scale clinical trial, comparing the effects of alendronate with placebo. They found that alendronate significantly increased bone mineral density at all skeletal sites, while placebo led to decreases. Furthermore, alendronate was associated with a significant reduction in the incidence of vertebral fractures.
A Fortress of Bone: The Power of Alendronate
This finding, like building a fortress against the harsh desert winds, demonstrates the effectiveness of alendronate in strengthening bones and reducing the risk of fractures.
Navigating the Desert of Osteoporosis
This research, like a beacon of hope in the desert of osteoporosis, underscores the importance of preventative measures to maintain bone health. It highlights the potential benefits of alendronate in reducing fracture risk and improving quality of life for postmenopausal women.
Dr. Camel's Conclusion
Alendronate, like a sturdy fortress built in the desert of osteoporosis, offers a powerful tool for strengthening bones and reducing fracture risk. This study reminds us that proactive measures can make a significant difference in maintaining bone health and navigating the challenges of osteoporosis.
Date :
- Date Completed 1995-12-01
- Date Revised 2022-04-08
Further Info :
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