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Very low dose danazol for relief of endometriosis-associated pelvic pain: a pilot study.

Author: BramanteT, CrosignaniP G, MauroF, PanazzaS, TrespidiL, VercelliniP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Very low dose danazol may be an effective alternative for temporary relief of endometriosis-associated pain.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To evaluate the efficacy and safety of very low dose danazol in improving pelvic pain in women with endometriosis, the benefit of preceding the treatment by a short course of a GnRH agonist, symptoms recurrence after drug withdrawal, and variations in menstrual pattern. DESIGN: Open-lab...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7525359

データ提供：米国国立医学図書館（NLM）

Danazol for Endometriosis: A New Oasis in the Desert of Pain

The desert of endometriosis, my dear friend, is a place of pain and discomfort. This condition, characterized by the growth of endometrial tissue outside the uterus, can cause severe pelvic pain. This study explores the potential of low-dose danazol as a treatment option for endometriosis-associated pelvic pain.

Danazol's Role in Pain Management

The study found that low-dose danazol, administered for 9 months, provided significant relief from dysmenorrhea, deep dyspareunia, and nonmenstrual pain in women with endometriosis. However, the relief was temporary, and symptoms recurred after the drug was withdrawn.

A Temporary Oasis

While danazol may provide temporary relief from endometriosis-associated pain, it's important to remember that it does not cure the condition. The study also highlights the need for further research to evaluate the long-term effects of danazol on lipid profiles.

Dr. Camel's Conclusion

This research offers a glimmer of hope for women struggling with endometriosis-associated pain. While low-dose danazol provides temporary relief, it's important to approach this treatment with caution and to explore other long-term management strategies. Remember, the journey through the desert of endometriosis requires ongoing vigilance and a commitment to finding the most effective solutions.

Date :
  1. Date Completed 1994-12-27
  2. Date Revised 2017-09-20
Further Info :

Pubmed ID

7525359

DOI: Digital Object Identifier

S0015-0282(16)57175-1

Related Literature

Article Analysis
・Effective treatment of endometriosis
SNS
PICO Info
in preparation
Languages

English

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