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Original Abstract of the Article :
Seventeen male homosexual outpatients with limited but progressive AIDS-associated Kaposi's sarcoma (KS) of skin, lymph nodes, oral cavity, and gastrointestinum were consecutively enrolled in an open, nonrandomized, prospective study. Patients received low-dose IFN-alpha 2b (3 MIU t.i.w.) in combina...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/00042560-199510020-00007
データ提供:米国国立医学図書館(NLM)
Interferon-Alpha 2b and Zidovudine: A Promising Combination for AIDS-Associated Kaposi's Sarcoma
The fight against [AIDS-associated Kaposi's sarcoma (KS)] is a challenging journey, akin to navigating a vast and unforgiving desert. This research explores the [efficacy and safety] of a combination therapy using [low-dose interferon-alpha 2b] and [zidovudine] in patients with [early-stage AIDS-associated KS]. The study evaluated the [therapeutic effectiveness] of this approach in a [prospective cohort] of patients.
A New Path in the Desert of AIDS-Related Cancers
The study found that [65%] of patients experienced [complete or partial remission] of KS, with some experiencing [lasting remission] for over [24 months]. The researchers noted a strong correlation between [treatment response] and [pretreatment CD4+ lymphocyte counts], suggesting the importance of [immune status] in [treatment outcome]. The combination therapy was generally well tolerated, with [minimal hematologic side effects].
Hope on the Horizon for Patients with AIDS-Associated KS
This research provides evidence for a [promising therapeutic option] for [early-stage AIDS-associated KS]. The [combination therapy] of [low-dose interferon-alpha 2b] and [zidovudine] offers a potential path to [remission] and [improved quality of life] for patients facing this challenging condition. Further research is needed to refine treatment protocols and explore the long-term benefits of this approach.
Dr.Camel's Conclusion
Like a camel seeking an oasis in a desert, patients with AIDS-associated KS often face a journey marked by hardship and uncertainty. This research offers a ray of hope by demonstrating the potential of a combination therapy to provide relief and improve outcomes. It's a testament to the ongoing efforts to combat this challenging disease and find new pathways to healing.
Date :
- Date Completed 1995-10-24
- Date Revised 2019-10-23
Further Info :
Related Literature
English
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