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Treatment of depression in Parkinson's disease: a meta-analysis.

Author: KlaassenT, RozendaalN, SneijdersG H, VerheyF R, de VetH C, van PraagH M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

A meta-analysis of 12 controlled studies on treating depression in Parkinson's disease (PD) found limited evidence due to methodological limitations. Further research is needed to understand and treat depression in PD effectively.
Paper Details　
Original Abstract of the Article :
Despite a 40% prevalence of depression in idiopathic Parkinson's disease (PD), an extensive literature search found only 12 controlled studies of treatment efficacy. A meta-analysis of these was performed in pursuit of guidelines for pharmacological treatment. Articles were scored on a scale from 0 ...See full text at original site
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引用元：
https://doi.org/10.1176/jnp.7.3.281

データ提供：米国国立医学図書館（NLM）

Treating Depression in Parkinson's Disease: A Meta-Analysis

This research navigates the intricate desert of [Parkinson's disease (PD)] and the associated challenge of [depression], a common comorbidity that significantly impacts quality of life. The authors conducted a meta-analysis of controlled studies to assess the efficacy of [pharmacological treatment] for depression in individuals with PD. It's like a camel caravan seeking a solution to the challenging sandstorms of [depression] that often accompany the journey of [PD].

Limited Evidence for Pharmacological Treatment of Depression in PD

The meta-analysis revealed a [lack of robust evidence] supporting the use of [pharmacological interventions] to treat [depression] in PD. This underscores the need for [further research] in this area to develop effective treatment strategies. It's like searching for a well-hidden oasis of [effective treatments] within the vast desert of [PD and depression], requiring persistent exploration and careful investigation.

The Need for More Research

The findings highlight the importance of [clinical trials] to evaluate the efficacy of different treatment options for [depression] in PD. This research is crucial for improving patient care and gaining a deeper understanding of the complex interplay between these two conditions. It's like a team of explorers venturing into a vast and unknown desert, seeking to chart a new course towards [improved health and well-being] for individuals with PD and depression.

Dr. Camel's Conclusion

This research emphasizes the need for further investigation into effective treatments for depression in Parkinson's disease. The lack of robust evidence highlights the importance of continued research to improve the lives of individuals facing this challenging comorbidity.

Date :
  1. Date Completed 1995-12-06
  2. Date Revised 2007-11-15
Further Info :

Pubmed ID

7580184

DOI: Digital Object Identifier

10.1176/jnp.7.3.281

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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