The clinical impact of reported variance in potency of antipsychotic agents.

Author: DewanM J, KossM

Paper Details 
Original Abstract of the Article :
There is significant disagreement on the clinical equivalence (or potency) of antipsychotic agents, with up to 500% variance reported in texts. To address the extent and consequences of these discrepancies, we took a random sample of 18 common psychiatry, psychopharmacology and pharmacology texts fo...See full text at original site
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引用元:
https://doi.org/10.1111/j.1600-0447.1995.tb09773.x

データ提供:米国国立医学図書館(NLM)

Clinical Impact of Variance in Antipsychotic Potency

This study investigates the discrepancies in potency reporting for antipsychotic medications. The authors examined 18 commonly used textbooks in the fields of psychiatry, psychopharmacology, and pharmacology to compare their antipsychotic equivalence tables. They found significant variations in the reported equivalences for most antipsychotic agents, with some drugs exhibiting a 500% variance in potency. The study emphasizes the potential for these discrepancies to lead to medication misuse, including prescribing high-potency antipsychotics in doses higher than necessary. This misuse can result in decreased efficacy and increased side effects.

Discrepancies in Antipsychotic Potency Reporting

The study highlights the importance of standardizing potency reporting for antipsychotics to ensure accurate and safe medication use. The authors emphasize the need for a more consistent and transparent approach to potency reporting to prevent medication misuse and optimize patient care.

Health Implications and Life Applications

Misuse of antipsychotic medications can lead to adverse effects, potentially impairing patient well-being. This study underscores the need for clinicians to be aware of the discrepancies in potency reporting and to carefully consider the appropriate dosage for each patient based on individual needs.

Dr. Camel's Conclusion

This study reminds us that even in the vast desert of medical knowledge, there are still sandstorms of uncertainty. Just like a camel navigating a desert, we must be cautious and use our knowledge wisely to avoid getting lost in the shifting sands of misinterpretations.

Date :
  1. Date Completed 1995-08-30
  2. Date Revised 2019-08-15
Further Info :

Pubmed ID

7625202

DOI: Digital Object Identifier

10.1111/j.1600-0447.1995.tb09773.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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