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Manchester regional breast study. Preliminary results.

Author: LythgoeJ P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Simple mastectomy with or without radiotherapy did not affect survival in patients with stage I breast cancer, but radiotherapy reduced local recurrence. Stage II breast cancer patients treated with simple mastectomy and radiotherapy had similar survival rates to those treated with radical mastectomy.
Paper Details　
Original Abstract of the Article :
1020 patients with early breast cancer were treated between March, 1970, and October, 1975, according to a prospective clinical trial. The results have been recorded after a follow-up of two to seven years. 713 cases of clinical stage-1 cancer were randomly allocated to treatment by simple mastectom...See full text at original site
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引用元：
https://doi.org/10.1016/s0140-6736(78)90859-0

データ提供：米国国立医学図書館（NLM）

The Manchester Regional Breast Study: Illuminating the Path of Early Breast Cancer Treatment

Breast cancer is a complex and challenging disease, and the quest for effective treatments continues. This research presents the preliminary findings of the Manchester Regional Breast Study, a prospective clinical trial that investigated treatment strategies for early breast cancer. The study compared two treatment approaches: simple mastectomy with postoperative radiotherapy and simple mastectomy alone. The study aimed to determine the impact of early postoperative radiotherapy on survival and local recurrence rates in patients with early breast cancer.

Early Postoperative Radiotherapy: A Valuable Tool for Early Breast Cancer Management

The study found that early postoperative radiotherapy significantly reduced the incidence of local recurrence in patients with clinical stage-I breast cancer. This finding underscores the importance of this treatment modality in improving long-term outcomes for patients with early breast cancer. This research offers a valuable addition to the growing body of knowledge regarding the best practices for managing early breast cancer.

Navigating Breast Cancer Treatment: The Importance of Radiotherapy

This research emphasizes the crucial role of early postoperative radiotherapy in reducing the risk of local recurrence in patients with early breast cancer. This finding can guide healthcare professionals in making informed treatment decisions for their patients, potentially leading to improved outcomes. Just as a desert traveler relies on a compass to navigate, understanding the benefits of early radiotherapy can help physicians guide patients toward more successful treatment plans.

Dr.Camel's Conclusion

The Manchester Regional Breast Study provides valuable evidence for the efficacy of early postoperative radiotherapy in reducing the risk of local recurrence in patients with early breast cancer. This research highlights the importance of personalized treatment plans and underscores the need for continued research in this field. The study emphasizes the importance of considering all available treatment options to optimize outcomes for patients with breast cancer.

Date :
  1. Date Completed 1978-06-12
  2. Date Revised 2019-06-10
Further Info :

Pubmed ID

76750

DOI: Digital Object Identifier

10.1016/s0140-6736(78)90859-0

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

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