Paper Details

  1. Home
  2. Paper Details

Acute effects of deflazacort and prednisone on rates of mineralization and bone formation.

Author: AdamiS, BenetonM N, BertoldoF, KanisJ A, Lo CascioV, PoggiG, ZanolinM E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effects of corticosteroids on bone formation in humans, finding no significant differences between prednisone and deflazacort.
Paper Details　
Original Abstract of the Article :
The aims of this study were to determine (1) whether acute suppression of bone formation could be evaluated after the administration of corticosteroids in man by quantitative bone histomorphometry; and (2) whether there were significant differences between the effects of prednisone and its analog de...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/BF00296340

データ提供：米国国立医学図書館（NLM）

The Impact of Corticosteroids on Bone Health: A Tale of Two Drugs

Corticosteroids, a class of medications used to treat inflammation, are like a powerful desert wind that can impact bone health. This study investigates the effects of two corticosteroids, prednisone and deflazacort, on bone formation and mineralization. The researchers are exploring the potential impact of these drugs on bone health, much like observing the effects of a desert wind on the landscape.

Comparing the Effects of Two Corticosteroids

The researchers found that both prednisone and deflazacort, while effective in treating inflammation, can suppress bone formation, like a strong desert wind causing erosion. However, they found no significant differences in the impact of these two drugs on bone health.

Navigating the Desert of Bone Health

This research underscores the importance of understanding the potential side effects of corticosteroids. It's like learning to navigate the desert, understanding the risks of strong winds and seeking ways to minimize their impact. If you are taking corticosteroids, it's important to consult with your healthcare professional about potential risks and discuss ways to maintain bone health.

Dr.Camel's Conclusion

This research is a reminder that even powerful tools, like corticosteroids, can have unintended consequences. It's like understanding the double-edged sword of a desert wind, which can bring both life-giving rain and destructive storms. This study highlights the importance of careful consideration of medication side effects, even while benefiting from their therapeutic properties.

Date :
  1. Date Completed 1995-06-08
  2. Date Revised 2019-08-30
Further Info :

Pubmed ID

7736317

DOI: Digital Object Identifier

10.1007/BF00296340

Related Literature

Article Analysis
・Effects of deflazacort
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.