Case report: reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication.

Author: KrauseM, KrähenbühlS, KupferschmidtH, MeierP J, SauterB, WyssP A

Paper Details 
Original Abstract of the Article :
Pimozide is a diphenylpiperidine neuroleptic with well characterized cardiovascular side effects including QT prolongation. So far, life-threatening cardiac arrhythmias, in particular torsades de pointes, have not been described in patients treated with pimozide. The authors describe a patient in wh...See full text at original site
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引用元:
https://doi.org/10.1097/00000441-199506000-00003

データ提供:米国国立医学図書館(NLM)

Pimozide: A Case of Reversible QT Prolongation and Torsades de Pointes

This case report presents a rare but serious complication associated with pimozide, a neuroleptic drug. The authors describe a patient who developed torsades de pointes, a potentially life-threatening cardiac arrhythmia, after ingesting a significant dose of pimozide in a suicide attempt. This case underscores the importance of careful monitoring and awareness of potential cardiovascular side effects associated with pimozide use, a reminder that even seemingly safe medications can have unforeseen consequences.

Navigating the Unforeseen Terrain of Medication Side Effects

The case report highlights the importance of being vigilant for potential medication side effects, even those considered rare or unpredictable. Just as a desert traveler must be prepared for unexpected challenges, healthcare providers must be aware of the potential for unforeseen consequences, particularly with medications that can affect cardiovascular function. This case serves as a reminder to approach medication use with a nuanced understanding of its potential risks and benefits.

The Importance of Patient Monitoring and Cardiovascular Safety

The case report emphasizes the importance of careful patient monitoring, particularly for individuals taking medications that can affect the cardiovascular system. Healthcare providers should be vigilant in assessing patient symptoms and promptly addressing any concerns, particularly those related to heart rhythm or electrical activity. By navigating the complex terrain of medication use with knowledge, vigilance, and compassion, we can minimize the risk of unexpected adverse events and ensure the safety of our patients.

Dr. Camel's Conclusion

This case report highlights the potential for pimozide, a commonly used neuroleptic drug, to cause serious cardiovascular complications, underscoring the importance of careful patient monitoring and awareness of potential side effects.
Date :
  1. Date Completed 1995-07-06
  2. Date Revised 2019-07-17
Further Info :

Pubmed ID

7771501

DOI: Digital Object Identifier

10.1097/00000441-199506000-00003

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PICO Info
in preparation
Languages

English

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