Famciclovir for the treatment of acute herpes zoster: effects on acute disease and postherpetic neuralgia. A randomized, double-blind, placebo-controlled trial. Collaborative Famciclovir Herpes Zoster Study Group.

Author: BarbarashR A, BoonR, CunninghamA, HengM, JonesT, MarleyJ, NahlikJ E, ReaT, SaltzmanR, TyringS

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To document the effects of treatment with famciclovir on the acute signs and symptoms of herpes zoster and postherpetic neuralgia. DESIGN: A randomized, double-blind, placebo-controlled, multicenter trial. SETTING: 36 centers in the United States, Canada, and Australia. PATIENTS: 419 i...See full text at original site
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引用元:
https://doi.org/10.7326/0003-4819-123-2-199507150-00002

データ提供:米国国立医学図書館(NLM)

Famciclovir for Herpes Zoster: A Desert of Pain Relief

Herpes zoster, commonly known as shingles, can be a painful and debilitating condition, like a scorching sandstorm that leaves lasting scars. This study, like a team of researchers seeking a remedy for this condition, examines the effects of famciclovir, an antiviral medication, on the acute symptoms of herpes zoster and postherpetic neuralgia (PHN), a persistent pain that can follow the initial infection. The authors, using a randomized, double-blind, placebo-controlled trial, meticulously evaluate the efficacy and safety of famciclovir in treating these painful conditions.

Famciclovir: A Cool Oasis in the Desert of Herpes Zoster Pain

The study found that famciclovir, like a refreshing oasis in a scorching desert, effectively accelerates lesion healing, reduces the duration of viral shedding, and most importantly, significantly reduces the duration of PHN. The researchers observed that famciclovir recipients experienced a twofold faster resolution of PHN compared to placebo recipients. This finding, like a calming breeze in the desert, offers hope for patients suffering from the debilitating pain of PHN. The study also highlights the safety and tolerability of famciclovir, further strengthening its potential as a valuable treatment for herpes zoster and its associated pain.

Navigating the Desert of Herpes Zoster

This study offers valuable insights into the management of herpes zoster and its associated pain. The findings emphasize the importance of early treatment with famciclovir to effectively combat the condition and minimize the risk of long-term complications like PHN. The study is like a well-stocked caravan, providing clinicians with essential tools and knowledge to navigate the challenging desert of herpes zoster and its associated pain.

Dr. Camel's Conclusion

This study explores the potential of famciclovir to alleviate the pain and discomfort of herpes zoster, offering a promising solution to this challenging condition. The findings highlight the importance of early treatment and underscore the potential of famciclovir to provide a welcome oasis in the desert of herpes zoster pain.

Date :
  1. Date Completed 1995-07-13
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

7778840

DOI: Digital Object Identifier

10.7326/0003-4819-123-2-199507150-00002

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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