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Evaluation of the quality of life associated with zidovudine treatment in asymptomatic human immunodeficiency virus infection. The AIDS Clinical Trials Group.

Author: ColeB F, CottonD J, GelberR D, GoldhirschA, LenderkingW R, TestaM A, VolberdingP A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This paper discusses the need to consider the quality of life associated with zidovudine therapy for asymptomatic HIV-infected patients. The effects of adverse events and the benefits of delayed disease progression should be weighed to optimize treatment decisions.
Paper Details　
Original Abstract of the Article :
Zidovudine therapy is recommended for asymptomatic patients infected with the human immunodeficiency virus (HIV) who have fewer than 500 CD4+ cells per cubic millimeter. An analysis of the quality of life associated with therapy that integrated both the effects of adverse events and the benefits of ...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199403173301102

データ提供：米国国立医学図書館（NLM）

Zidovudine Therapy for Asymptomatic HIV Infection: A Quality of Life Perspective

The desert of HIV/AIDS research has been a constant source of innovation and discovery, with researchers tirelessly seeking effective treatments and prevention strategies. This study, published in 1996, investigates the impact of zidovudine therapy on the quality of life of asymptomatic HIV-infected patients. The study analyzed data from the AIDS Clinical Trials Group, evaluating the effects of adverse events and the benefits of delayed disease progression. The findings highlight the need to consider both the benefits and drawbacks of therapy when making treatment decisions for asymptomatic HIV-infected individuals.

Balancing Benefits and Drawbacks: A Careful Approach to Zidovudine Therapy

The study's findings underscore the importance of a comprehensive approach to evaluating the impact of zidovudine therapy on quality of life. While the drug offers potential benefits in delaying disease progression, it's essential to consider the potential for adverse events and their impact on patient well-being. This research emphasizes the need for open and honest conversations between patients and healthcare providers about the potential benefits and risks associated with zidovudine therapy, to make informed decisions based on individual needs and circumstances.

Navigating HIV Treatment: A Journey of Choice and Support

For individuals living with HIV, it's crucial to engage in a collaborative partnership with their healthcare provider to navigate the complexities of treatment and management. This study underscores the importance of personalized care plans that address both the physical and mental health needs of individuals living with HIV, considering both the benefits and potential drawbacks of therapy. It also highlights the importance of access to ongoing support and resources to navigate the emotional and social challenges associated with HIV infection.

Dr.Camel's Conclusion

This study provides a valuable perspective on the impact of zidovudine therapy on the quality of life of asymptomatic HIV-infected patients, highlighting the need for a careful assessment of both the benefits and potential drawbacks of treatment. It emphasizes the importance of personalized care and open communication between patients and healthcare providers to ensure the best possible outcomes for individuals living with HIV.

Date :
  1. Date Completed 1994-03-24
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7906386

DOI: Digital Object Identifier

10.1056/NEJM199403173301102

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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