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5-ASA enema versus oral sulphasalazine in maintaining remission in ulcerative colitis.

Author: AndreoliA, LevensteinS, PranteraC, SpinellaS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

This study compared the efficacy of biweekly high-dose 5-aminosalicylic acid (5-ASA) enemas with oral sulphasalazine in maintaining remission in patients with left-sided ulcerative colitis. Both treatments were effective in maintaining remission, with no significant differences between the two, suggesting that biweekly 5-ASA enemas may be a viable alternative to oral sulphasalazine.
Paper Details　
Original Abstract of the Article :
This prospective trial in patients with left-sided ulcerative colitis evaluated the efficacy and acceptability of biweekly high-dose 5-aminosalicylic acid (5-ASA) enemas (4g/100ml) in maintaining a remission recently induced using daily 5-ASA enemas. Thirty-one patients were randomly assigned, 16 to...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/7914759

データ提供：米国国立医学図書館（NLM）

Maintaining Remission in Ulcerative Colitis: 5-ASA Enema vs. Oral Sulfasalazine

Ulcerative colitis is a chronic inflammatory bowel disease that can significantly disrupt life. This research compares the effectiveness of two different 5-aminosalicylic acid (5-ASA) treatments - biweekly high-dose 5-ASA enemas and oral sulphasalazine - in maintaining remission in patients with left-sided ulcerative colitis. The study followed patients for six months, evaluating both clinical and endoscopic outcomes. This research is like a comparative study of two different oasis strategies in the desert of ulcerative colitis, seeking to determine the most effective way to maintain remission.

5-ASA Enema: A Promising Option for Maintaining Remission

The study found that biweekly 5-ASA enemas were at least as effective as oral sulphasalazine in maintaining remission in patients with left-sided ulcerative colitis. This finding offers a promising alternative for patients seeking to manage their condition. It's like discovering a new oasis strategy in the desert of ulcerative colitis treatment, offering a potentially more convenient and effective way to maintain remission.

Navigating the Desert of Ulcerative Colitis Treatment

This research underscores the importance of exploring different treatment options for ulcerative colitis. It highlights the need for individualized approaches that consider patient preferences and specific needs. It's like navigating the vast and challenging desert of ulcerative colitis treatment, seeking the best path to long-term health and well-being.

Dr.Camel's Conclusion

This study provides valuable insights into the management of ulcerative colitis. The researchers have meticulously compared two different treatment approaches, revealing a promising new strategy for maintaining remission. It's a reminder that in the desert of chronic illness, finding the right oasis can make all the difference in achieving long-term health and well-being.

Date :
  1. Date Completed 1994-09-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

7914759

DOI: Digital Object Identifier

7914759

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