Efficacy and tolerance of long-term, high-dose gabapentin: additional observations.

Author: HandforthA, TreimanD M

Paper Details 
Original Abstract of the Article :
Gabapentin (GBP) has shown antiepileptic efficacy and good tolerance in clinical trials. Much remains to be learned about its clinical use. As a participating center in the US Gabapentin Study Group, we report observations that have practical implications for patient management. Twenty-three patient...See full text at original site
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引用元:
https://doi.org/10.1111/j.1528-1157.1994.tb02551.x

データ提供:米国国立医学図書館(NLM)

Gabapentin: A Long-Term Solution for Intractable Seizures

Intractable seizures, those that are resistant to conventional treatment, can be a devastating condition. This study investigates the efficacy and tolerance of long-term, high-dose gabapentin (GBP) in patients with intractable partial-onset seizures. The researchers report observations from a clinical trial, examining the effectiveness and safety of GBP when used as an add-on therapy in patients who have not responded well to other antiepileptic drugs (AEDs).

Gabapentin: A Promising Long-Term Treatment for Intractable Seizures

The study demonstrates the long-term efficacy and good tolerance of GBP in treating intractable seizures. In the majority of patients, GBP effectively controlled seizures for extended periods, even at high doses. While some patients experienced adverse events, these were generally mild and manageable. The findings suggest that GBP can be a valuable tool for managing intractable seizures, offering long-term seizure control and improving quality of life for patients.

A Beacon of Hope for Intractable Seizures: Gabapentin's Potential

This research is like a desert oasis, offering hope for patients struggling with intractable seizures. GBP emerges as a promising long-term treatment option, demonstrating efficacy and good tolerance. This study provides valuable insights for physicians and patients, highlighting the potential of GBP for improving seizure control and enhancing quality of life for individuals with intractable seizures.

Dr.Camel's Conclusion

Intractable seizures are like a sandstorm, relentless and difficult to control. This study provides a glimpse of hope, revealing GBP's potential as a long-term solution. Like a desert nomad finding a wellspring of water, patients with intractable seizures may find relief and improved quality of life with GBP.

Date :
  1. Date Completed 1994-11-21
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

7925148

DOI: Digital Object Identifier

10.1111/j.1528-1157.1994.tb02551.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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