An evaluation of the potential side-effects of alpha-glucosidase inhibitors used for the management of diabetes mellitus.

Author: ReuserA J, WisselaarH A

Paper Details 
Original Abstract of the Article :
Orally taken alpha-glucosidase inhibitors are used for the management of diabetes mellitus. These drugs can prevent the postprandial rise of the blood glucose level by inhibiting the enzymatic digestion of carbohydrates in the intestinal lumen. Non-absorbable inhibitors such as acarbose are expected...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2362.1994.tb02251.x

データ提供:米国国立医学図書館(NLM)

Alpha-Glucosidase Inhibitors: A Closer Look at Potential Side Effects

Alpha-glucosidase inhibitors, a class of medications used to manage diabetes mellitus, work by inhibiting the breakdown of carbohydrates in the intestines, thereby reducing postprandial blood glucose levels. This literature review examines the potential side effects of these drugs, focusing on the differences between non-absorbable inhibitors, such as acarbose, and absorbable inhibitors, such as miglitol.

A Closer Look at the Potential Side Effects: Navigating the Landscape of Alpha-Glucosidase Inhibitors

The review highlights the potential side effects associated with absorbable alpha-glucosidase inhibitors, such as miglitol. While non-absorbable inhibitors are expected to function exclusively in the intestines, absorbable inhibitors may exert an inhibitory effect on alpha-glucosidases present in other tissues. The review concludes that miglitol is generally safe when taken at recommended doses but cautions against its use in individuals with kidney dysfunction.

Navigating Diabetes Management: Choosing the Right Approach

This review provides valuable information for clinicians managing diabetes patients. The study highlights the potential side effects of absorbable alpha-glucosidase inhibitors and offers guidance on their safe and appropriate use. It emphasizes the importance of considering individual patient factors, such as kidney function, when choosing the most suitable treatment approach.

Dr.Camel's Conclusion

This review, like a compass guiding travelers through the desert of diabetes management, provides valuable insights into the potential side effects of alpha-glucosidase inhibitors. The authors highlight the importance of carefully considering the individual patient's needs and ensuring that the chosen medication is both effective and safe.

Date :
  1. Date Completed 1995-01-25
  2. Date Revised 2019-08-25
Further Info :

Pubmed ID

8001622

DOI: Digital Object Identifier

10.1111/j.1365-2362.1994.tb02251.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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