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[Comparison of nisoldipine and diltiazem in the treatment of effort angina pectoris].

Author: CicatielloA M, De RosaM L, LombardiL, PandolfiE, RengoF, SantamariaF, SestitoM, VozaA, de CaprioL, di PalmaA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Nisoldipine, like diltiazem, was an effective drug in the treatment of stable effort angina, increasing exercise tolerance and reducing angina frequency and nitrate consumption.
Paper Details　
Original Abstract of the Article :
BACKGROUND: In order to evaluate the benefits of a calcium-antagonist medium-term treatment, 20 patients with effort stable angina pectoris were treated with nisoldipine in comparison to diltiazem. METHODS: Twenty patients with stable effort angina completed a double-blind, placebo controlled trial...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8013763

データ提供：米国国立医学図書館（NLM）

Nisoldipine vs Diltiazem for Effort Angina: A Comparative Trial

Effort angina, a chest pain that occurs during physical activity, can significantly impact quality of life. This study compares the effectiveness of two calcium-channel blockers, nisoldipine and diltiazem, in treating effort angina. The authors conducted a double-blind, placebo-controlled trial, evaluating exercise tolerance, angina frequency, nitrate consumption, and side effects in patients with stable effort angina. Their findings provide valuable insights into the efficacy of these medications in managing this common cardiovascular condition.

Effective Angina Management: Comparing Nisoldipine and Diltiazem

The study found that both nisoldipine and diltiazem significantly improved exercise tolerance, reduced angina frequency, and decreased nitrate consumption. Both drugs also effectively reduced rate-pressure product at submaximal exercise. These findings demonstrate the effectiveness of both nisoldipine and diltiazem in managing effort angina. However, the study did not find any significant differences between the two drugs, suggesting that both may be equally effective options for treating stable effort angina.

Navigating the Angina Landscape: Selecting the Right Treatment

This study provides clinicians with valuable information for navigating the treatment landscape of effort angina. The authors' findings demonstrate the effectiveness of both nisoldipine and diltiazem, suggesting that either medication could be a suitable choice for patients with stable effort angina. The choice of medication may be influenced by factors such as individual patient preferences, potential drug interactions, and cost considerations.

Dr.Camel's Conclusion

The treatment of effort angina is like a desert journey, with multiple pathways leading to relief. This study helps us to navigate these pathways, comparing the effectiveness of nisoldipine and diltiazem. Both drugs prove their worth in managing angina, suggesting that clinicians have a range of options to guide their patients towards a more comfortable and fulfilling life.

Date :
  1. Date Completed 1994-07-26
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8013763

DOI: Digital Object Identifier

8013763

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in preparation
Languages

Italian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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