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Effects of antihypertensive medications on quality of life in elderly hypertensive women.

Author: BaumeR M, ColtonT, CroogS H, EliasM F, HallW D, JenkinsC D, LeiblumS R, PerryH M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effects of atenolol, enalapril, and isradipine on quality of life in elderly hypertensive women. All three drugs effectively controlled blood pressure and did not negatively impact quality of life.
Paper Details　
Original Abstract of the Article :
The impact of antihypertensive medications on the quality of life of elderly hypertensive women has rarely been systematically evaluated in large clinical trials using drugs from the new generations of pharmaceutic preparations. We carried out a multicenter, randomized double-blind clinical trial wi...See full text at original site
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引用元：
https://doi.org/10.1093/ajh/7.4.329

データ提供：米国国立医学図書館（NLM）

Antihypertensive Medications and Quality of Life: A Focus on Elderly Women

The search for [effective antihypertensive medications] that [minimize side effects and maintain quality of life] is a priority, particularly for [elderly hypertensive women]. This study aimed to assess the impact of [atenolol, enalapril, and isradipine] on [quality of life measures] in a group of [309 hypertensive women aged 60 to 80 years]. The researchers employed a [multicenter, randomized double-blind clinical trial] over a [22-week period] to compare the effects of these medications on [well-being, physical status, emotional status, cognitive functioning, and social role participation]. Their findings offer valuable insights into the impact of these commonly prescribed antihypertensive medications on the quality of life of elderly women.

Antihypertensive Medications Effectively Control Blood Pressure with Minimal Impact on Quality of Life

The study demonstrated that [all three medications effectively controlled blood pressure] with [no significant differences in quality of life measures] between the groups. The researchers observed [minimal side effects], with only [a worsening of cough in enalapril patients and dry mouth in atenolol patients] being statistically significant. This suggests that these medications can effectively manage hypertension without compromising the quality of life of elderly women.

Considerations for Managing Hypertension in Elderly Women

This study provides reassurance that [atenolol, enalapril, and isradipine] can be used effectively to control blood pressure in elderly women while minimizing potential negative impacts on their quality of life. However, it is crucial to [monitor for potential side effects] and [individualize treatment plans] to ensure optimal outcomes for each patient.

Dr. Camel's Conclusion

Imagine a desert oasis where the gentle breeze carries the scent of healing herbs, representing the restorative power of antihypertensive medication. This study confirms that these medications can effectively manage blood pressure in elderly women, allowing them to continue enjoying the journey of life with renewed vigor.

Date :
  1. Date Completed 1994-08-12
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

8031548

DOI: Digital Object Identifier

10.1093/ajh/7.4.329

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Article Analysis
・Side Effects of isradipine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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