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Cefaclor vs amoxicillin in the treatment of acute, recurrent, and chronic sinusitis.

Author: FergusonR T, GrayD W, HuckW, LundG K, MosterM B, NielsenR W, ReedB D, ZoBellD H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This double-blind, randomized trial compared cefaclor and amoxicillin in the treatment of acute, recurrent, and chronic maxillary sinusitis. The study involved 108 adult patients with acute, recurrent, or chronic maxillary sinusitis. The results showed a high rate of clinical improvement in patients with acute sinusitis, but the rate was less favorable in those with recurrent and chronic disease regardless of the drug used.
Paper Details　
Original Abstract of the Article :
BACKGROUND: The treatment of acute, recurrent, and chronic sinusitis remains controversial because of the presence of a wide variety of aerobic and anaerobic bacteria in the sinuses. DESIGN: This double-blind, randomized trial compared cefaclor with amoxicillin in the treatment of acute, recurrent,...See full text at original site
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引用元：
https://doi.org/10.1001/archfami.2.5.497

データ提供：米国国立医学図書館（NLM）

Cefaclor vs. Amoxicillin for Sinusitis: A Double-Blind Trial

The treatment of sinusitis, a common ailment that affects the sinuses, is often a challenging journey. This research delves into the effectiveness of two antibiotics, cefaclor and amoxicillin, in treating acute, recurrent, and chronic sinusitis. The study utilized a double-blind, randomized trial to compare the effectiveness of these treatments, providing a controlled environment for evaluating their efficacy. The study found that both antibiotics were effective in treating acute sinusitis but were less effective in treating recurrent and chronic sinusitis.

Seeking a Cure in the Sinusitis Desert

This study found that while both cefaclor and amoxicillin were effective in treating acute sinusitis, neither antibiotic consistently yielded positive results in the treatment of recurrent or chronic sinusitis. This suggests that different treatment strategies might be needed for these more persistent forms of the condition.

Navigating the Sinusitis Landscape

Sinusitis can be a perplexing condition to treat. This research sheds light on the varying effectiveness of cefaclor and amoxicillin in treating different forms of the condition. It suggests that a more targeted approach may be necessary to address the unique characteristics of each form of sinusitis.

Dr.Camel's Conclusion

This study provides valuable insights into the treatment of sinusitis. The findings highlight the need for further research to develop more effective treatments for recurrent and chronic sinusitis, which can be particularly challenging to manage.

Date :
  1. Date Completed 1994-04-06
  2. Date Revised 2019-10-23
Further Info :

Pubmed ID

8118565

DOI: Digital Object Identifier

10.1001/archfami.2.5.497

Related Literature

Article Analysis
・Effective treatment of sinusitis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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