Minocycline for prophylaxis of infection with Neisseria meningitidis: high rate of side effects in recipients.

Author: AltmanR, BlackK, DrewT M, GoldfieldM

Paper Details 
Original Abstract of the Article :
A high rate of side effects (mostly vestibular) was found among 83 people receiving prophylaxis with minocycline because of contact with a patient who had died of meningitis due to Neisseria meningitidis. Three groups of contacts received different lots of minocycline and different dosage regimens. ...See full text at original site
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引用元:
https://doi.org/10.1093/infdis/133.2.194

データ提供:米国国立医学図書館(NLM)

Minocycline: A Double-Edged Sword

The use of antibiotics for prophylaxis against infectious diseases is a delicate balancing act, and this study explores the potential risks and benefits of minocycline in preventing meningococcal infection. The researchers, like adventurers navigating a treacherous desert, conducted a study involving 83 individuals who received minocycline prophylaxis due to contact with a patient who had died of meningococcal meningitis. Their findings highlight a high rate of side effects, primarily vestibular in nature. This study, like a cautionary tale etched in the sands of time, emphasizes the importance of careful consideration and risk-benefit analysis before administering minocycline for prophylactic purposes.

Balancing Benefits and Risks: An Important Consideration

The study's findings, like a compass guiding decision-making, emphasize the critical importance of weighing the benefits and risks associated with minocycline prophylaxis. The high rate of side effects necessitates cautious use, especially in individuals with pre-existing vestibular conditions. This research, like a weathered map revealing hidden dangers, underscores the need for individualized decision-making in the use of antibiotics.

The Quest for Safer Prophylaxis: A Continuing Journey

This research, like a desert oasis offering respite from the harsh elements, highlights the ongoing need for safer and more effective prophylactic measures against meningococcal infection. This study encourages further research into alternative approaches, minimizing the risk of side effects while maximizing the potential for effective prevention.

Dr.Camel's Conclusion

This research, like a caravan journey through a vast desert, underscores the complexity of antibiotic use in infectious disease prevention. The study serves as a reminder that even seemingly straightforward interventions can come with unforeseen consequences. The quest for safe and effective prophylactic strategies remains a priority in the ever-shifting sands of medical research.

Date :
  1. Date Completed 1976-04-02
  2. Date Revised 2019-05-09
Further Info :

Pubmed ID

812929

DOI: Digital Object Identifier

10.1093/infdis/133.2.194

Related Literature

SNS
PICO Info
in preparation
Languages

English

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