A comparison of the efficacy of topical tretinoin and low-dose oral isotretinoin in rosacea.

Author: ErtlG A, KligmanA M, LevineN

Paper Details 
Original Abstract of the Article :
Twenty-two patients with severe or recalcitrant rosacea were divided into three treatment groups in a randomized, double-blind trial that compared low-dose oral isotretinoin (10 mg/d), topically applied tretinoin (0.025% cream), and the combined use of both isotretinoin and tretinoin. For the first ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8129410

データ提供:米国国立医学図書館(NLM)

Tretinoin vs. Isotretinoin: A Battle for Rosacea Relief

Rosacea, a chronic skin condition that can leave the face flushed and bumpy, can be a source of frustration for many. This study, published in the journal [Journal Name], compares the effectiveness of two popular treatments for rosacea: topical tretinoin and low-dose oral isotretinoin.

The study, a randomized, double-blind trial, involved 22 patients with severe or recalcitrant rosacea. The participants were divided into three groups: one receiving low-dose oral isotretinoin (10 mg/d), another receiving topical tretinoin (0.025% cream), and the last receiving a combination of both. The study spanned 32 weeks, with a 16-week period for each treatment regimen followed by a 16-week period where isotretinoin was withheld and tretinoin or a placebo was continued.

The results, like a refreshing spring amidst the desert, showed that both tretinoin and low-dose isotretinoin were effective in treating rosacea. The combined treatment did not offer any significant additional benefits compared to the individual treatments. This study provides valuable insights into the effectiveness of different treatment options for rosacea, helping dermatologists navigate the desert of treatment choices.

Choosing the Right Treatment for Rosacea: A Balancing Act

The study's findings highlight the importance of individualized treatment approaches for rosacea. Based on the severity of the condition and individual patient preferences, dermatologists can make informed decisions about using either topical tretinoin or low-dose oral isotretinoin to achieve optimal results.

Navigating the Desert of Rosacea: A Guide for Patients

If you find yourself navigating the desert of rosacea, remember that you're not alone. Consulting a dermatologist can help you find the most effective treatment for your specific needs. This study provides a valuable roadmap for understanding the effectiveness of different treatment options, empowering you to work with your doctor to find the right path to clear skin.

Dr.Camel's Conclusion

This study provides valuable insights into the treatment of rosacea. While both tretinoin and low-dose isotretinoin have proven effective, the best treatment choice will depend on individual patient needs and preferences. It's important to consult with a dermatologist to develop a personalized treatment plan that aligns with your unique situation.

Date :
  1. Date Completed 1994-04-14
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8129410

DOI: Digital Object Identifier

8129410

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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