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Original Abstract of the Article :
28 myelomeningocele patients (aged 2-30 years) with clinical symptoms of acute UTI participated in this open uncontrolled clinical trial at the Orthopedic University Hospital of Heidelberg (Dir.: Prof. Dr. H. Cotta). 4 patients were treated with 200 mg cefixime tablets bid, 24 patients received 4 mg...See full text at original site
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引用元:
https://doi.org/10.1055/s-2008-1046575
データ提供:米国国立医学図書館(NLM)
Cefixime: A Potential Solution for Urinary Tract Infections in Myelomeningocele Patients
Urinary tract infections (UTIs) can be particularly challenging to manage in patients with myelomeningocele, a birth defect affecting the spinal cord. This research explores the effectiveness and safety of cefixime, an oral cephalosporin antibiotic, in treating UTIs in this patient population. The study involved a group of 28 myelomeningocele patients with acute UTIs, who were treated with cefixime for a duration of 6 to 10 days. The researchers carefully monitored both clinical and microbiological responses to treatment. Their findings indicate that cefixime is an efficient and well-tolerated treatment option for complicated UTIs in myelomeningocele patients.
Cefixime Demonstrates Efficacy in Managing UTIs in Myelomeningocele Patients
The study revealed that 88% of the patients experienced complete recovery from their UTI within 5 to 9 days after completing the cefixime treatment. This positive outcome suggests that cefixime can effectively combat bacterial infections in this complex patient group. The researchers also found that cefixime successfully eliminated the baseline pathogens in 96% of the patients. However, a small percentage of patients experienced reinfection, highlighting the need for continued monitoring and potential follow-up treatment.
Navigating UTIs: A Reminder of Good Hygiene Practices
This research reinforces the importance of maintaining good hygiene practices to prevent UTIs, especially in vulnerable populations like those with myelomeningocele. It also highlights the need for careful monitoring and follow-up after treatment to ensure that infections are fully resolved.
Dr. Camel's Conclusion
Treating UTIs in patients with myelomeningocele can feel like navigating a winding desert trail, fraught with potential obstacles. This study offers a glimmer of hope, demonstrating the effectiveness and safety of cefixime in addressing this challenging condition. While cefixime provides a valuable tool, remember that maintaining good hygiene practices is crucial for preventing UTIs, especially in vulnerable populations. Let's keep exploring new paths toward better UTI management for all those who need it.
Date :
- Date Completed 1994-05-12
- Date Revised 2013-11-21
Further Info :
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