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[Hormone therapy before radical prostatectomy. Effects on surgical method and resection margins. Belgian Uro-Oncological Study Group (B.U.O.S.)].

Author: AckaertK, BaertL, De RidderD, ElgamalA, OyenR, Van PoppelH, Van de VoordeW, WerbrouckP

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Preoperative hormonal treatment with estramustine phosphate for 6 weeks before radical prostatectomy significantly reduced the number of positive surgical margins in patients with clinical stage T2 prostate cancer. However, this benefit was not observed in patients with clinical stage T3 prostate cancer.
Paper Details　
Original Abstract of the Article :
127 patients with a clinical stage T2b and T3 prostate cancer were randomized in order to undergo either a radical prostatectomy alone or a radical prostatectomy after hormonal treatment (560 mg of estramustine phosphate daily for 6 weeks) in a prospective multi-center study. The clinical or radiolo...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8197931

データ提供：米国国立医学図書館（NLM）

Hormone Therapy: A New Approach to Prostate Cancer

The [treatment] of [prostate cancer] is a dynamic landscape, constantly evolving as researchers seek more effective and less invasive therapies. This study explores the potential of [hormonal therapy] in [prostate cancer]. Researchers investigated the effects of [estraustine phosphate] on [surgical outcomes] and [resection margins] in a group of patients with [clinical stage T2b and T3 prostate cancer]. The findings highlight the potential benefits of [hormonal therapy] in improving [surgical outcomes] for patients with [prostate cancer].

Hormonal Therapy: A Potential Advantage for Prostate Cancer Patients

This study, like a well-charted oasis in a vast desert, provides valuable insights into the potential of [hormonal therapy] in [prostate cancer treatment]. The researchers' findings suggest that [preoperative hormonal treatment] may improve [surgical outcomes] for patients with [clinical stage T2 prostate tumors].

A New Frontier in Prostate Cancer Treatment: Hormonal Therapy

This study, like a beacon of hope in a challenging landscape, underscores the potential of [hormonal therapy] in the treatment of [prostate cancer]. The researchers' findings suggest that [estraustine phosphate] may offer a valuable tool for optimizing [surgical outcomes] and improving [resection margins] for patients with [prostate cancer]. It's a reminder that even in the vast and complex desert of [cancer treatment], innovative approaches continue to emerge, offering new hope for patients.

Dr.Camel's Conclusion

This research provides a compelling case for the potential benefits of [hormonal therapy] in the management of [prostate cancer]. The study's findings suggest that [estraustine phosphate] may enhance [surgical outcomes] and improve [resection margins] for patients with [prostate cancer]. This research is a testament to the continuous quest for new and effective treatment options in the ongoing battle against [cancer].

Date :
  1. Date Completed 1994-06-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8197931

DOI: Digital Object Identifier

8197931

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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