[Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients].

Author: ChibaS, FujiiR, MeguroH, MoriA, MoriT, NumazakiK, SatohY, SunakawaK, TerashimaI, ToyonagaY

Paper Details 
Original Abstract of the Article :
Carnitine metabolism was studied in 16 pediatric patients with various infections under the treatment with cefditoren pivoxil (CDTR-PI) in granular form. Pivalic acid released from pivaloyloxymethyl ester of the drug was metabolized to pivaloylcarnitine. As results, an increase in urinary carnitine ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8254895

データ提供:米国国立医学図書館(NLM)

Cefditoren Pivoxil and Carnitine Metabolism: Insights from Pediatric Patients

The world of pediatric medicine is a delicate desert, requiring a nuanced understanding of how medications interact with young, developing bodies. This study investigates the effects of cefditoren pivoxil (CDTR-PI) on carnitine metabolism in pediatric patients. Researchers monitored 16 children with various infections while they were treated with CDTR-PI, studying how the drug affected their carnitine levels.

Cefditoren Pivoxil: A Transient Impact on Carnitine Metabolism

The study found that CDTR-PI had a temporary impact on carnitine metabolism in the children, resulting in increased urinary carnitine excretion and decreased serum carnitine levels. These changes were reversible upon cessation of treatment, suggesting that the effects are temporary and likely not cause for concern. This discovery provides crucial information for physicians treating pediatric patients with CDTR-PI.

Navigating the Desert of Pediatric Care

This study emphasizes the importance of understanding drug interactions and potential side effects in children. It underscores the need for careful monitoring and tailored approaches to pediatric care. Remember, a camel's journey through the desert requires both strength and agility, and treating children is no different. We must approach each case with care and precision.

Dr.Camel's Conclusion

This study provides a valuable insight into the delicate balance of carnitine metabolism in children. It reminds us that the desert of pediatric care requires careful navigation, especially when administering medications. As we continue to explore this vast landscape, we'll gain a deeper understanding of how to best care for our youngest patients.
Date :
  1. Date Completed 1994-01-12
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

8254895

DOI: Digital Object Identifier

8254895

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PICO Info
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Languages

Japanese

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