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Patterns of failure following loco-regional radiotherapy in the treatment of limited stage small cell lung cancer.

Author: ArnoldA, CoyP, DixonP, EvansW K, HodsonD I, KostashukE, MurrayN, PaterJ L, PayneD G, ZeeB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This report discusses the theoretical basis for minimizing the development of treatment resistance in tumors, such as small cell lung cancer (SCLC), by using all treatment modalities early in the treatment program.
Paper Details　
Original Abstract of the Article :
The probability of treatment resistant cells developing in a tumor, such as small cell lung cancer (SCLC) which has a rapid cell cycle time, is a function of the number of tumor cells present and of time. Theoretically, the development of resistance to chemotherapy and radiotherapy should be minimiz...See full text at original site
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引用元：
https://doi.org/10.1016/0360-3016(94)90058-2

データ提供：米国国立医学図書館（NLM）

Patterns of Failure Following Loco-Regional Radiotherapy in the Treatment of Limited Stage Small Cell Lung Cancer

The treatment of [limited stage small cell lung cancer (SCLC)] is an area of ongoing research and development. This study investigates the [patterns of failure] following [loco-regional radiotherapy] in patients with limited stage SCLC. It aims to understand the mechanisms of treatment resistance and to identify potential strategies for improving outcomes. This research is a valuable contribution to the field of oncology, offering insights into the challenges and opportunities of treating SCLC.

The Challenge of Treatment Resistance: Unraveling the Patterns of Failure

The study reveals that treatment resistance, a common challenge in SCLC, can arise from the rapid cell cycle time of this aggressive cancer. The development of resistance is influenced by both the number of tumor cells present and the duration of treatment. This study underscores the importance of early and aggressive treatment strategies to minimize the risk of treatment failure. This research is a reminder that the battle against cancer requires a multi-faceted approach, combining various therapies and targeting treatment strategies to individual patient needs.

Optimizing Treatment Strategies: A Multi-faceted Approach

This study highlights the need for a multi-faceted approach to treating SCLC, combining various therapeutic modalities and tailoring treatment strategies to individual patient characteristics. Early detection and timely intervention are essential to maximizing treatment effectiveness and improving outcomes for patients with this challenging cancer. This research is a testament to the ongoing pursuit of better treatment options and the dedication of healthcare professionals to improving the lives of cancer patients.

Dr.Camel's Conclusion

This study is like a desert caravan, navigating the vast and complex terrain of cancer treatment. It reveals the challenges of treatment resistance and the importance of early intervention. This research is a reminder that the journey to conquer cancer requires a collaborative effort, combining innovative therapies, personalized care, and a unwavering commitment to improving patient outcomes.

Date :
  1. Date Completed 1994-02-09
  2. Date Revised 2019-07-08
Further Info :

Pubmed ID

8276650

DOI: Digital Object Identifier

10.1016/0360-3016(94)90058-2

Related Literature

Article Analysis
・Effective treatment of lung cancer
SNS
PICO Info
in preparation
Languages

English

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