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Nortriptyline in the hospitalized elderly: tolerance and side effect reduction.

Author: MulsantB H, PollockB G, RosenJ, SweetR

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Nortriptyline (NT) was generally well tolerated in elderly depressed inpatients. Bethanechol effectively reduced antimuscarinic side effects associated with NT.
Paper Details　
Original Abstract of the Article :
This article describes two separate but related studies regarding the use of nortriptyline (NT) in the treatment of depressed elderly inpatients. The first study assesses medication tolerance to NT during the acute treatment of late-life depression. The second describes a placebo-controlled study of...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8290682

データ提供：米国国立医学図書館（NLM）

Nortriptyline: A Desert Oasis for Elderly Depression

Depression in older adults presents unique challenges, often requiring careful medication management to ensure both efficacy and safety. This study explores the use of nortriptyline (NT) in hospitalized elderly patients with depression, focusing on its tolerability and potential side effects. The researchers, like careful guides leading a caravan through a desert landscape, analyzed the impact of NT on elderly patients with depression. Their findings suggest that NT can be a safe and effective treatment option for elderly patients, with appropriate monitoring and strategies to manage potential side effects.

Nortriptyline in Elderly Patients: Managing the Desert Sands

This study highlights the potential of nortriptyline (NT) as a safe and effective treatment option for depression in hospitalized elderly patients. However, it's important to be aware of potential side effects and to manage them effectively. Think of it like a desert traveler needing to navigate a challenging terrain, being mindful of potential obstacles and taking appropriate precautions to ensure a safe and successful journey.

Navigating Depression in Later Life

This research offers valuable insights for healthcare professionals managing depression in elderly patients. It demonstrates that nortriptyline (NT) can be a viable treatment option, but careful monitoring and effective management of potential side effects are essential. This is like leading a caravan through a vast desert landscape, where attention to detail and preparation are key to achieving a successful outcome.

Dr.Camel's Conclusion

This study highlights the potential of nortriptyline (NT) as a safe and effective treatment option for depression in hospitalized elderly patients, emphasizing the importance of careful monitoring and effective management of potential side effects. It's like a desert oasis offering a haven for weary travelers, but one that requires vigilance and attention to detail to ensure a safe and successful journey.

Date :
  1. Date Completed 1994-02-23
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8290682

DOI: Digital Object Identifier

8290682

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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