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Behavioral response to buspirone in cocaine and phencyclidine withdrawal.

Author: FoltsD J, GianniniA J, GrahamB H, LoiselleR H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Buspirone is a drug that was found to be effective in treating cocaine and phencyclidine (PCP) withdrawal.
Paper Details　
Original Abstract of the Article :
The effects of buspirone in treating cocaine and phencyclidine (PCP) withdrawal were studied. Withdrawal symptoms of these two street-drugs are thought to be due to norepinephrine, dopamine and possibly serotonin depletion. Buspirone acts by enhancing dopaminergic and noradrenergic firing as well by...See full text at original site
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引用元：
https://doi.org/10.1016/0740-5472(93)90055-7

データ提供：米国国立医学図書館（NLM）

Buspirone for Cocaine and Phencyclidine Withdrawal: A Behavioral Study

This study explores the potential of buspirone, a drug commonly used to treat anxiety, in alleviating the challenging symptoms of cocaine and phencyclidine (PCP) withdrawal. Like a camel traversing the desolate terrain of addiction, the researchers sought to understand the role of buspirone in managing these withdrawal symptoms. The study, which involved 32 cocaine abusers and 24 PCP abusers, found that buspirone significantly improved symptoms of cocaine withdrawal, with notable effects observed from the fifth day onward. The researchers also noted that buspirone displayed delayed effectiveness in PCP withdrawal, attributing this to the complex effects of PCP on the nervous system. This study provides valuable insights into the potential therapeutic applications of buspirone in treating drug withdrawal, suggesting that this medication could play a crucial role in supporting individuals during this challenging period.

Buspirone: A Potential Treatment Option for Drug Withdrawal

The study's findings, like a beacon of hope in the desert of addiction, suggest that buspirone could be a viable treatment option for individuals experiencing cocaine and PCP withdrawal. The researchers observed a significant improvement in symptoms of cocaine withdrawal with buspirone treatment, suggesting that this medication could provide much-needed relief and support during this challenging period. The study's findings highlight the need for further research to explore the potential of buspirone as a treatment for drug withdrawal, with a focus on understanding its specific effects and optimal dosage.

Dr.Camel's Conclusion

This study explores the potential of buspirone as a treatment for cocaine and PCP withdrawal, offering a glimmer of hope in the vast and often desolate landscape of addiction. The research findings suggest that buspirone could provide valuable support to individuals struggling with these challenging conditions, potentially improving their quality of life and facilitating their recovery. By carefully considering the potential benefits and limitations of this medication, we can work towards finding effective solutions for individuals battling addiction and its debilitating effects.

Date :
  1. Date Completed 1994-03-15
  2. Date Revised 2019-10-23
Further Info :

Pubmed ID

8308936

DOI: Digital Object Identifier

10.1016/0740-5472(93)90055-7

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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