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Efficacy and safety of pravastatin once daily in primary moderate hypercholesterolemia: the Israeli experience.

Author: BeigelY, BrookG, EisenbergS, FainaruM, HaratsD, LevyY, RubinsteinA, SkurnikY

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Pravastatin is a drug used to lower cholesterol levels. In a 26-week, placebo-controlled study of 77 patients with hypercholesterolemia, pravastatin was found to reduce total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol. Pravastatin was well tolerated and caused only mild side effects.
Paper Details　
Original Abstract of the Article :
Seventy-seven hypercholesterolemic patients participated in a 26-week, multicenter, randomized, double-blind, placebo-controlled study that investigated the efficacy and safety of pravastatin therapy. All patients had primary moderate hypercholesterolemia (total cholesterol 200-300 mg/dl, at the end...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8314685

データ提供：米国国立医学図書館（NLM）

Efficacy and Safety of Pravastatin Once Daily in Primary Moderate Hypercholesterolemia

This research investigates the efficacy and safety of pravastatin, a statin medication, in treating primary moderate hypercholesterolemia. The study, a [randomized controlled trial] involving [77 hypercholesterolemic patients], compared pravastatin therapy with placebo. The authors found that pravastatin significantly reduced total cholesterol, LDL cholesterol, and triglycerides while increasing HDL cholesterol. The drug was generally well-tolerated, with minimal side effects. These findings suggest that pravastatin is an effective and safe treatment option for primary moderate hypercholesterolemia.

Pravastatin: A Valuable Tool for Cholesterol Management

The study's findings demonstrate the effectiveness of pravastatin in lowering cholesterol levels and improving lipid profiles. The drug's efficacy in reducing LDL cholesterol, a key risk factor for cardiovascular disease, is particularly noteworthy. This suggests that pravastatin could be a valuable tool for managing cholesterol levels and reducing the risk of heart disease. It's like finding a cool oasis in the desert, offering a refreshing respite from the heat and dryness of high cholesterol.

Navigating Cholesterol Management with Pravastatin

This research highlights the potential of pravastatin as an effective and safe treatment option for hypercholesterolemia. The study's findings underscore the importance of managing cholesterol levels to reduce the risk of heart disease. It's like navigating a desert with a reliable camel – pravastatin can help us manage the challenges of high cholesterol and reach our destination safely and comfortably.

Dr. Camel's Conclusion

This study provides valuable insights into the efficacy and safety of pravastatin for treating hypercholesterolemia. The findings suggest that pravastatin can be an effective tool for lowering cholesterol levels and improving lipid profiles, potentially reducing the risk of heart disease. It's like finding a refreshing oasis in the desert, offering a source of relief and support for those facing the challenges of high cholesterol.

Date :
  1. Date Completed 1993-07-29
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8314685

DOI: Digital Object Identifier

8314685

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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