Paper Details
- Home
- Paper Details
[Clinical evaluation of imipenem/cilastatin sodium and fosfomycin as second-line combination chemotherapy in severe infections associated with hematologic disorders].
Author: HoriikeS, KashimaK, KuzuyamaY, MisawaS, NakaiH, SeriuT, TakashimaT, TanakaS, TaniwakiM, TsudaS
Original Abstract of the Article :
Imipenem/cilastatin sodium (IPM/CS) which is a broad-spectrum agent against both Gram-positive and -negative bacteria was used in combination with fosfomycin (FOM) as a second-line chemotherapy for severe infections associated with hematologic disorders. FOM was partnered with IPM because FOM may en...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/8331778
データ提供:米国国立医学図書館(NLM)
Imipenem/Cilastatin Sodium and Fosfomycin: A Combined Approach to Severe Infections in Hematologic Disorders
Severe infections pose a significant threat to individuals with hematologic disorders, often weakening their immune system. This study investigates the effectiveness of a combined chemotherapy regimen involving imipenem/cilastatin sodium (IPM/CS) and fosfomycin (FOM) in treating severe infections associated with hematologic disorders. The researchers analyzed the efficacy and safety of this combination therapy in a group of patients.Combined Chemotherapy: A Promising Approach
The study found that IPM/CS plus FOM showed an overall efficacy rate of 61% in treating severe infections in hematologic disorders. The combination therapy was particularly effective in patients with sepsis and those with low peripheral granulocyte counts. The study also reported that the combination therapy was generally well-tolerated, with only mild side effects such as nausea.A Beacon of Hope for Patients with Hematologic Disorders
Just like finding a freshwater oasis in the middle of a vast desert, this research offers a promising approach to treating severe infections in individuals with compromised immune systems. This study encourages further research into the combined use of IPM/CS and FOM as a potential treatment option for this challenging patient population.Dr. Camel's Conclusion
The desert is a place of extremes, where life can be precarious. This study reminds us that facing complex medical challenges often requires innovative approaches. This research offers a beacon of hope for individuals struggling with severe infections, highlighting the potential of combined therapy as a valuable tool in the fight against these debilitating conditions.Date :
- Date Completed 1993-08-17
- Date Revised 2016-11-16
Related Literature
Article Analysis
SNS
PICO Info
in preparation
Languages
Japanese
Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.