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Comparison of prochlorperazine and lorazepam antiemetic regimens in the control of postchemotherapy symptoms.

Author: MadsenR W, RhodesV A, SimmsS G

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Lorazepam significantly reduces total posttherapy symptom experience in patients receiving noncisplatin chemotherapy, suggesting its value in antiemetic regimens.
Paper Details　
Original Abstract of the Article :
This randomized, double-blind crossover study was undertaken to compare the antiemetic effectiveness of intravenous prochlorperazine (Compazine) and lorazepam (Ativan) in the management of postchemotherapy symptoms during two initial cycles of therapy. Each patient received at least one treatment as...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8337162

データ提供：米国国立医学図書館（NLM）

Combatting Chemotherapy Side Effects: A Head-to-Head Comparison of Antiemetic Regimens

This randomized, double-blind crossover study compared the effectiveness of intravenous prochlorperazine and lorazepam in managing post-chemotherapy symptoms. The authors found that both regimens effectively controlled nausea and vomiting, but lorazepam significantly reduced overall symptom experience, particularly fatigue and pain. This study highlights the importance of considering individual patient needs and symptom profiles when selecting antiemetic regimens to optimize comfort and quality of life during chemotherapy.

Tailoring Antiemetic Therapies: A Personalized Approach

This study underscores the importance of personalized medicine in managing chemotherapy side effects. The authors' findings demonstrate the need for careful assessment of patient needs and symptom profiles when selecting antiemetic regimens, allowing for a more tailored approach to symptom management.

Managing Chemotherapy Side Effects: A Focus on Comfort

This study emphasizes the importance of improving the comfort and quality of life of patients undergoing chemotherapy. The authors' findings highlight the potential benefits of lorazepam in reducing overall symptom experience, potentially contributing to a more positive treatment experience.

Dr. Camel's Conclusion

This study offers a valuable roadmap for managing chemotherapy side effects, emphasizing the importance of individualized treatment plans and the potential benefits of lorazepam. Imagine a compassionate oasis in the desert of chemotherapy side effects, offering patients relief and improving their quality of life during treatment.

Date :
  1. Date Completed 1993-08-25
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

8337162

DOI: Digital Object Identifier

8337162

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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