[Scavenging effects of cyproheptadine on oxygen free radicals].

Author: XinH B, ZhangB H

Paper Details 
Original Abstract of the Article :
The scavenging effects of cyprohepdadine (Cyp), an antiserotonin-antihistaminic agent with significant calcium channel blocker activity, on oxygen free radicals were studied. Cyp was found to significantly scavenge the hydroxyl radical (.OH) produced by Fenton reaction (Fe(2+)+H2O2) (EC50 = 54 mumol...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8368073

データ提供:米国国立医学図書館(NLM)

Cyproheptadine: A Desert Oasis for Oxygen Free Radicals

This study investigates the potential of cyproheptadine (Cyp), a versatile medication known for its antihistamine and antiserotonin properties, in combating the damaging effects of oxygen free radicals. Much like a camel adapting to the harsh conditions of the desert, Cyp demonstrates its resilience by effectively scavenging hydroxyl radicals and inhibiting their generation. This research explores Cyp's protective role in preventing myocardial injury, suggesting that its antioxidant properties may play a significant role in mitigating damage caused by free radicals. The study highlights the importance of understanding the complex interplay between oxidative stress and cellular health.

Unleashing the Power of Antioxidants: Cyproheptadine's Role in Combating Free Radicals

The study found that Cyp exhibited potent scavenging activity against hydroxyl radicals, even surpassing the efficacy of mannitol, a known hydroxyl radical scavenger. This finding suggests that Cyp's ability to neutralize these reactive oxygen species may contribute to its protective effects against heart damage. This research underscores the potential of antioxidants like Cyp in safeguarding against oxidative stress and promoting cellular health.

A Beacon of Hope in the Desert of Oxidative Stress

The study reveals Cyp's potential as a powerful antioxidant, offering a beacon of hope in the desert of oxidative stress. As free radicals can contribute to various diseases, understanding their intricate mechanisms and exploring effective countermeasures, such as the use of antioxidants like Cyp, is essential for promoting overall health and well-being.

Dr. Camel's Conclusion

This research highlights the intriguing potential of cyproheptadine in combating the damaging effects of oxygen free radicals. Much like a desert oasis provides respite from the harsh sun, Cyp offers protection against oxidative stress, which is a major contributor to various diseases. Understanding the intricate mechanisms of oxidative stress and exploring effective countermeasures, such as the use of antioxidants, is essential for safeguarding health and longevity.

Date :
  1. Date Completed 1993-10-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8368073

DOI: Digital Object Identifier

8368073

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Languages

Chinese

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