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Long-term outcome after acute treatment with alprazolam or clonazepam for panic disorder.
Author: CohenL S, Meltzer-BrodyS, OttoM W, PollackM H, RosenbaumJ F, TesarG E
Original Abstract of the Article :
The relative effectiveness of the available treatments for panic disorder may best be understood in the context of the longitudinal course of the disorder. This study examines a number of clinically relevant issues, including long-term outcome after acute treatment, the proportion of patients remain...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/8376613
データ提供:米国国立医学図書館(NLM)
The Long-Term Impact of Alprazolam and Clonazepam for Panic Disorder
Panic disorder is a debilitating anxiety disorder characterized by recurrent panic attacks. Benzodiazepines, such as alprazolam and clonazepam, are often used to treat panic disorder, but their long-term effectiveness and potential for dependence are areas of concern. This study examined the long-term outcome of patients with panic disorder who received acute treatment with alprazolam or clonazepam in a previous controlled trial.
Managing Panic Disorder: A Long-Term Perspective
The study found that most patients maintained benefit with long-term benzodiazepine pharmacotherapy, but a significant proportion required additional treatment strategies, such as multiple medications or nonpharmacologic interventions. The study also noted that the average dosage of alprazolam and clonazepam did not increase over time. The authors identified several predictors of both acute and long-term response to treatment, including pre-treatment severity of symptoms, presence of dysthymia, and the presence of comorbid anxiety disorders.
Navigating the Complexities of Anxiety Disorders
As a psychiatrist, I'm constantly seeking ways to provide effective and sustainable treatment for anxiety disorders. This study highlights the complexities of managing panic disorder, emphasizing the need for long-term monitoring and individualized treatment approaches. It underscores the importance of addressing comorbid conditions, such as dysthymia and social phobia, in order to optimize treatment outcomes. This research is like a compass in the desert, guiding us through the intricate pathways of anxiety disorders and helping us find the best possible treatment solutions for our patients.
Dr.Camel's Conclusion
This study offers valuable insights into the long-term management of panic disorder, highlighting the need for a comprehensive and individualized approach. It reminds us that treating anxiety disorders often requires a combination of pharmacotherapy and nonpharmacologic interventions, tailored to the specific needs of each individual. It's a reminder that the journey towards mental well-being is a continuous process of discovery, adaptation, and support.
Date :
- Date Completed 1993-10-21
- Date Revised 2013-11-21
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