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Effect of conventional dose growth hormone therapy for two years on height velocity and height prognosis in girls with Turner syndrome.

Author: HakulinenA, KäärM L, LenkoH L, MäenpääJ, MäkeläA L, SipiläI

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the use of growth hormone (GH) therapy in girls with Turner syndrome, a genetic disorder that affects growth. The study found that GH therapy significantly increased height velocity in these girls, although the long-term effects on final height are unknown. GH therapy was well-tolerated.
Paper Details　
Original Abstract of the Article :
The aims of this national multicentre study in Finland were to evaluate whether the height velocity of patients with Turner syndrome would increase with the conventional human growth hormone (GH) therapy regimen normally given to GH-deficient children and whether girls with Turner syndrome actually ...See full text at original site
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引用元：
https://doi.org/10.1159/000182758

データ提供：米国国立医学図書館（NLM）

Growth Hormone Therapy for Turner Syndrome: Positive Results, Ongoing Questions

This study investigates the effects of conventional growth hormone (GH) therapy on height velocity and height prognosis in girls with Turner syndrome. The research involved a multi-center study in Finland, where girls with Turner syndrome received GH therapy for two years. The results show a significant increase in height velocity during the two-year treatment period, suggesting that GH therapy can be effective in promoting growth in these girls. However, the long-term impact of GH therapy on final height remains to be determined, requiring further research and follow-up studies.

Unlocking Growth Potential: GH Therapy Shows Positive Effects

The study suggests that conventional GH therapy can effectively promote growth in girls with Turner syndrome, improving their height velocity and overall growth potential. This finding is encouraging, offering hope for improved outcomes in individuals with this condition. However, the long-term impact on final height remains an area requiring further investigation and longitudinal studies.

Navigating Growth and Development: A Holistic Approach

The study underscores the importance of early diagnosis and appropriate interventions for individuals with Turner syndrome. While GH therapy shows promising results in promoting growth, a holistic approach that includes genetic counseling, comprehensive medical monitoring, and individualized treatment plans is crucial for addressing the diverse needs of these individuals.

Dr.Camel's Conclusion

Like a camel navigating a vast desert, growth hormone therapy can help individuals with Turner syndrome traverse the challenges of growth and development. This study offers a promising oasis in the landscape of Turner syndrome treatment, highlighting the potential benefits of GH therapy. However, like the desert, there are still areas that require further exploration to fully understand the long-term effects and optimize treatment outcomes.
Date :
  1. Date Completed 1993-09-30
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

8395455

DOI: Digital Object Identifier

10.1159/000182758

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English

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