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Stiripentol in atypical absence seizures in children: an open trial.

Author: AndersonG D, FarwellJ R, KerrB M, LevyR H, TorJ A

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Stiripentol (STP) was effective in reducing atypical absence seizures in 10 children, with an average decrease of 70%. The most common side effects were anorexia, nausea, vomiting, and lethargy.
Paper Details　
Original Abstract of the Article :
Stiripentol (STP) was added to the antiepileptic drug (AED) regimen of 10 patients with uncontrolled atypical absence seizures (more than one seizure a day). Seven boys and three girls aged 6-16 years participated in the study. Concomitant AEDs included various combinations of phenobarbital (PB), ph...See full text at original site
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引用元：
https://doi.org/10.1111/j.1528-1157.1993.tb02416.x

データ提供：米国国立医学図書館（NLM）

Stiripentol: A Potential Treatment for Atypical Absence Seizures in Children

Atypical absence seizures (AAS) can be a challenging neurological condition, particularly in children. This study explores the potential benefits of stiripentol (STP), an antiepileptic drug, in treating AAS. The researchers conducted an open trial involving 10 children with uncontrolled AAS. The study found that STP significantly reduced the frequency of AAS in all patients, demonstrating its potential efficacy as an adjunctive therapy. The study highlights the importance of further clinical trials to evaluate the long-term effectiveness and safety of STP in treating AAS.

Stiripentol: A Potential Oasis in the Desert of AAS

This research suggests that STP could offer a valuable treatment option for children with uncontrolled AAS, providing relief from this debilitating condition and improving their quality of life. The study’s findings provide hope for families navigating the challenging landscape of epilepsy.

Finding Relief in the Desert of Epilepsy

Epilepsy can be a challenging condition, like a relentless desert storm. This study offers a potential solution, highlighting the promising effects of STP in treating AAS and providing hope for patients and their families.

Dr.Camel's Conclusion

This research explores the potential benefits of stiripentol in treating atypical absence seizures in children. It offers hope for families navigating the challenging desert of epilepsy, providing a potential oasis of relief and improved quality of life.

Date :
  1. Date Completed 1993-04-20
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

8453942

DOI: Digital Object Identifier

10.1111/j.1528-1157.1993.tb02416.x

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Article Analysis
・Side Effects of stiripentol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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