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Efficacy of slow-release oral isradipine in moderate-to-severe hypertension with add-on spirapril.
Author: AbarquezR F, CastilloR R, SyR G
Original Abstract of the Article :
The new slow-release oral formulation (SRO) of isradipine, a dihydropyridine calcium antagonist, was evaluated in 57 patients who had moderate-to-severe hypertension following a 2-week wash-out period and a 2-week placebo period. The angiotensin-converting enzyme (ACE) inhibitor spirapril, at a dose...See full text at original site
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引用元:
https://doi.org/10.1093/ajh/6.3.77s
データ提供:米国国立医学図書館(NLM)
Isradipine: A Slow-Release Solution for Hypertension
High blood pressure, also known as hypertension, is a common condition that can significantly impact cardiovascular health. This study evaluates the efficacy of a slow-release oral formulation of isradipine, a calcium channel blocker, in patients with moderate to severe hypertension. The authors investigated the effectiveness of isradipine alone and in combination with spirapril, an angiotensin-converting enzyme (ACE) inhibitor, in controlling blood pressure.
A Dual Approach to Blood Pressure Management
The study found that isradipine alone effectively normalized blood pressure in a significant portion of the patients. For those who did not achieve complete blood pressure control, adding spirapril to the treatment regimen further improved blood pressure regulation. This finding suggests that a combination approach, involving both a calcium channel blocker and an ACE inhibitor, may be beneficial for some patients with moderate to severe hypertension.
Finding the Right Path: A Balanced Approach to Treatment
The study highlights the importance of personalized treatment strategies for managing hypertension. Just as a camel navigates the desert, seeking the most efficient path to reach its destination, so too must we carefully consider the various treatment options for hypertension. This may involve a single medication or a combination approach, tailored to the specific needs of each individual.
Dr. Camel's Conclusion
The study on isradipine for hypertension underscores the importance of finding the right treatment combination to effectively manage this common condition. Just as a wise camel knows when to seek out a watering hole in the desert, so too must we find the right combination of treatments to achieve optimal blood pressure control and protect our cardiovascular health.
Date :
- Date Completed 1993-05-10
- Date Revised 2019-05-12
Further Info :
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