Hepatitis C RNA in liver of chronic hepatitis C patients before and after interferon alfa treatment.

Author: BalartL A, DashS, GerberM A, PerrilloR, RegensteinF, RoddenberryJ, ShiehY S, ShimK S, TaylorB

Paper Details 
Original Abstract of the Article :
BACKGROUND: Successful treatment of chronic hepatitis C with interferon alfa is frequently followed by relapse. Because loss of hepatitis C viral RNA (HCV-RNA) in serum is not predictive of sustained response, the loss of HCV-RNA in liver as a predictor of sustained response was investigated. METHO...See full text at original site
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引用元:
https://doi.org/10.1016/0016-5085(93)90358-j

データ提供:米国国立医学図書館(NLM)

Hepatitis C: A Desert Storm in the Liver

Hepatitis C, a viral infection that can cause chronic liver disease, is like a persistent desert storm that can leave lasting damage. This research, like an expedition seeking to understand the intricate workings of this disease, investigated the presence of hepatitis C viral RNA (HCV-RNA) in the liver of patients with chronic hepatitis C before and after treatment with interferon alfa. The authors, like skilled desert explorers, sought to uncover the relationship between HCV-RNA levels in the liver and treatment outcomes. The study, like a journey through a complex and ever-changing landscape, revealed that HCV-RNA disappearance from the liver was associated with a higher likelihood of a sustained response to treatment, although relapse was still possible.

A Glimpse of Hope: Tracking HCV-RNA in the Liver

This research, like a beacon in the desert, offers hope for individuals struggling with hepatitis C. The study's findings, like a map revealing hidden pathways, suggest that monitoring HCV-RNA levels in the liver could potentially provide valuable insights into treatment outcomes. However, the authors caution that the disappearance of HCV-RNA from the liver does not guarantee a sustained response, highlighting the need for continued monitoring and follow-up care.

Navigating the Desert of Hepatitis C: A Long and Challenging Journey

This research, like a journey through the desert, reminds us of the complexity of hepatitis C and the ongoing challenges in managing this condition. While the study offers valuable insights into the relationship between HCV-RNA levels and treatment outcomes, it also underscores the need for continued research to develop more effective and long-lasting therapies. This research, like a desert oasis offering temporary relief, emphasizes the importance of a multi-faceted approach to combatting hepatitis C and improving the lives of individuals living with this chronic disease.

Dr.Camel's Conclusion

This research, a valuable contribution to the field of hepatology, provides insights into the complex relationship between HCV-RNA levels in the liver and treatment outcomes in hepatitis C. The study's findings, like a compass guiding us through the desert of hepatitis C, highlight the importance of monitoring HCV-RNA levels and underscore the need for ongoing research to develop more effective and long-lasting therapies. This research, like a desert oasis reminding us of the importance of perseverance, encourages continued efforts to combat this challenging disease and improve the lives of individuals affected by hepatitis C.

Date :
  1. Date Completed 1993-06-03
  2. Date Revised 2019-07-07
Further Info :

Pubmed ID

8482458

DOI: Digital Object Identifier

10.1016/0016-5085(93)90358-j

Related Literature

SNS
PICO Info
in preparation
Languages

English

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