Concentrations of nitrogen mustard in the air during topical treatment of patients with mycosis fungoides.

Author: CooijmansA C, MeulenbeltJ, PoelJ, Van VlotenW A

Paper Details 
Original Abstract of the Article :
Acute and chronic side-effects have been reported during topical treatment of mycosis fungoides with nitrogen mustard (HN2). In order to estimate the risk for the nurse applying topical HN2, the concentration of HN2 in the air during treatment was measured. Air samples were obtained before, and duri...See full text at original site
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引用元:
https://doi.org/10.1111/j.1365-2133.1993.tb00199.x

データ提供:米国国立医学図書館(NLM)

Nitrogen Mustard: Navigating the Desert of Mycosis Fungoides Treatment

The treatment of mycosis fungoides, a rare type of cutaneous T-cell lymphoma, often involves the use of nitrogen mustard, a potent chemotherapy agent. This study delves into the potential risks associated with topical application of nitrogen mustard, exploring the concentration levels of the drug in the air during treatment. Imagine a desert traveler venturing into a hazardous area, carefully monitoring the environment for potential dangers.

The researchers measured the concentration of nitrogen mustard in the air during topical treatment of patients with mycosis fungoides. They found that the mean concentration of nitrogen mustard in the air during the 20-minute treatment period was 0.036 mg/m3. While this concentration is below the maximal allowable concentration (MAC) value for sulphur mustard, the researchers emphasize the importance of minimizing exposure for nursing staff.

Protecting the Oasis of Health: Minimizing Exposure to Nitrogen Mustard

This study highlights the importance of careful safety protocols when administering topical nitrogen mustard. The researchers' findings underscore the need for appropriate protective measures, such as wearing gloves and masks, to minimize exposure to this potent drug. Healthcare providers should prioritize the safety of both patients and staff during treatment.

Living with Mycosis Fungoides: A Journey Through the Desert of Uncertainty

Mycosis fungoides is a complex and challenging condition, often requiring a combination of therapies and ongoing monitoring. This study emphasizes the importance of understanding the potential risks and benefits of treatment options, such as nitrogen mustard. It is crucial for patients to engage in open communication with their healthcare providers to develop a personalized treatment plan that minimizes the risk of side effects while maximizing the potential for successful management.

Dr. Camel's Conclusion

This study provides valuable insights into the potential risks associated with topical application of nitrogen mustard. The researchers' findings underscore the importance of careful safety protocols and the need for healthcare providers to prioritize the safety of both patients and staff during treatment. While nitrogen mustard remains a valuable tool in the management of mycosis fungoides, it is essential to approach this treatment with caution and to carefully assess the risks and benefits for each individual patient.

Date :
  1. Date Completed 1993-06-24
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

8494753

DOI: Digital Object Identifier

10.1111/j.1365-2133.1993.tb00199.x

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SNS
PICO Info
in preparation
Languages

English

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