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Investigation on the efficacy and tolerance of azelastine (HCL) nasal spray versus ebastine tablets in patients with seasonal allergic rhinitis.

Author: Conde HernándezJ, Delgado RomeroJ, Palma AguilarJ L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Azelastine nasal spray was as effective as Ebastine tablets in treating seasonal allergic rhinitis. Both drugs had good tolerance and minimal side effects.
Paper Details　
Original Abstract of the Article :
We compared the efficacy and tolerance of Azelastine nasal spray (0.14 mg in each nostril twice a day) versus Ebastine tablets (10 mg) as a single night dose in a Phase IV open, randomized, parallel-group clinical trial lasting 14 days, conducted with 63 patients diagnosed of seasonal allergic rhini...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8526167

データ提供：米国国立医学図書館（NLM）

Comparing Azelastine Nasal Spray and Ebastine Tablets for Seasonal Allergic Rhinitis

In the realm of [allergy research], finding effective and well-tolerated treatments for [seasonal allergic rhinitis] is a constant quest. This study, like a camel navigating a sandstorm, delves into the efficacy and tolerability of two medications: Azelastine nasal spray and Ebastine tablets. The researchers used a [Phase IV open, randomized, parallel-group clinical trial] involving [63 patients] diagnosed with [seasonal allergic rhinitis] to compare the two treatments. The researchers evaluated a range of symptoms, including sneezing, nasal itching, runny nose, nasal congestion, and eye irritation, using a [4-point scale] to gauge severity. The study found that both treatments were equally effective in controlling symptoms and reducing airway resistance, with no significant differences between the two groups.

Azelastine Nasal Spray: A Promising Treatment for Seasonal Allergies

The results suggest that Azelastine nasal spray is a promising treatment for [seasonal allergic rhinitis], offering comparable efficacy to Ebastine tablets with excellent tolerability and minimal side effects.

Navigating the Desert of Allergies

This research offers valuable insights into the treatment of [seasonal allergies]. It's crucial to remember that everyone reacts differently to medications, and what works for one person might not work for another. Consulting a doctor to determine the best treatment plan is always the most effective way to navigate the desert of allergies.

Dr.Camel's Conclusion

Azelastine nasal spray emerges as a viable treatment option for seasonal allergic rhinitis, offering comparable efficacy to ebastine tablets with an excellent safety profile. This research underscores the importance of individualizing treatment plans for allergic disorders, reflecting the unique needs of each patient.

Date :
  1. Date Completed 1996-01-22
  2. Date Revised 2012-11-15
Further Info :

Pubmed ID

8526167

DOI: Digital Object Identifier

8526167

Related Literature

Article Analysis
・Effects of azelastine nasal spray
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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