Paper Details

  1. Home
  2. Paper Details

Oral type II collagen treatment in early rheumatoid arthritis. A double-blind, placebo-controlled, randomized trial.

Author: AltenR, BraunJ, EggensU, HiepeF, HügeW, KaryS, KühneA, ListingJ, MitchisonN A, SieperJ, SörensenH, UlbrichN, ZinkA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Oral type II collagen was only effective in a minority of patients with early rheumatoid arthritis (RA). Further research is needed to identify patients who are most likely to respond to this therapy.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To investigate the efficacy of oral type II collagen in the treatment of early rheumatoid arthritis (RA). METHODS: Ninety patients with RA (disease duration < or = 3 years) were treated for 12 weeks with oral bovine type II collagen at 1 mg/day (n = 30) or 10 mg/day (n = 30) or with plac...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/art.1780390106

データ提供：米国国立医学図書館（NLM）

Oral Type II Collagen for Early Rheumatoid Arthritis: A Double-Blind Trial

Rheumatoid arthritis (RA), a chronic inflammatory disease that affects the joints, is like a sandstorm, relentlessly eroding the smooth functioning of the body. This study, published in the field of [研究分野], examines the effectiveness of oral type II collagen as a treatment for early RA. The researchers conducted a double-blind, placebo-controlled, randomized trial involving [研究手法] to investigate whether oral type II collagen can alleviate RA symptoms. Their findings indicated that [主要な発見], suggesting that oral type II collagen may have a limited role in treating early RA. A particularly noteworthy finding was that [特筆すべき結果や意義].

Type II Collagen: A Shifting Oasis in the RA Landscape

The results of this study suggest that oral type II collagen may not be a universal solution for early RA. While a small number of patients showed positive responses, the overall impact was limited. These findings remind us that finding effective treatments for RA can be as challenging as navigating a shifting desert landscape, requiring constant exploration and adaptation.

Seeking a Stable Oasis in the Storm of RA: Personalized Approaches

This study highlights the need for personalized approaches to treating RA. What works for one patient may not work for another. A comprehensive understanding of individual factors, including disease severity and genetic predisposition, is essential for developing effective therapies. It's like searching for a stable oasis in the storm of RA, where each individual requires a unique path to find relief.

Dr. Camel's Conclusion

This double-blind trial offers valuable insights into the potential role of oral type II collagen in treating early RA. While the results suggest limited efficacy, they emphasize the importance of individualizing treatment approaches to achieve optimal outcomes for patients battling this complex and challenging disease.

Date :
  1. Date Completed 1996-02-12
  2. Date Revised 2019-07-18
Further Info :

Pubmed ID

8546737

DOI: Digital Object Identifier

10.1002/art.1780390106

Related Literature

Article Analysis
・Effective treatment of rheumatoid arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.