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Ovarian irradiation and prednisone following surgery and radiotherapy for carcinoma of the breast.

Author: AlltW E, BealeF A, BulbrookR D, BushR S, ClarkR M, FitzpatrickP J, HawkinsN V, HaywardJ L, JenkinR D, MeakinJ W, PanzarellaT, PringleJ F, RiderW D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A randomized study of 703 patients with operable breast cancer following mastectomy found that ovarian irradiation combined with prednisone significantly delayed recurrence and prolonged survival compared to no further therapy or ovarian irradiation alone. This benefit was particularly observed in premenopausal women aged 45 years or more.
Paper Details　
Original Abstract of the Article :
Following mastectomy, patients aged 35 to 76 years with operable breast cancer underwent postoperative irradiation of the chest wall and regional lymph nodes. They were then assigned at random to receive no further therapy (NT), ovarian irradiation (R) 2000 rads in 5 days, or ovarian irradiation in ...See full text at original site
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引用元：
https://doi.org/10.1007/BF01806627

データ提供：米国国立医学図書館（NLM）

Ovarian Irradiation and Breast Cancer: A Desert of Challenges and Hope

Dr. Camel has a deep respect for the resilience of individuals facing the challenges of cancer. This study examines the effects of ovarian irradiation and prednisone following surgery and radiotherapy for breast cancer. The researchers investigate the long-term impact of these treatments on recurrence and survival in patients with operable breast cancer.

Navigating the Desert of Breast Cancer: Exploring Treatment Options

This research reveals the potential benefits of ovarian irradiation combined with prednisone therapy in delaying recurrence and prolonging survival in premenopausal patients with breast cancer. The study provides valuable insights into the long-term effects of these treatments, offering guidance for clinicians making treatment decisions.

Finding the Oasis of Hope: Supporting Patients with Breast Cancer

Dr. Camel encourages patients with breast cancer to discuss treatment options with their physicians. This study highlights the importance of personalized care and collaborative decision-making in navigating the complexities of breast cancer treatment.

Dr. Camel's Conclusion

This study provides valuable insights into the long-term effects of ovarian irradiation and prednisone therapy in patients with breast cancer. The research emphasizes the importance of individualized treatment approaches and underscores the need for ongoing research to optimize cancer treatment strategies.

Date :
  1. Date Completed 1996-10-18
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

8750523

DOI: Digital Object Identifier

10.1007/BF01806627

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・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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