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A controlled trial of oral acyclovir for iridocyclitis caused by herpes simplex virus. The Herpetic Eye Disease Study Group.

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Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Oral acyclovir, in conjunction with topical corticosteroids and trifluridine, may be beneficial in the treatment of HSV iridocyclitis. Although the study was underpowered, the trend in the results suggests a potential benefit.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To assess the benefit of adding oral acyclovir to a regimen of topical prednisolone phosphate and trifluridine for the treatment of iridocyclitis caused by herpes simplex virus (HSV). METHODS: Patients with HSV iridocyclitis were enrolled in a multicenter controlled clinical trial suppor...See full text at original site
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引用元：
https://doi.org/10.1001/archopht.1996.01100140267002

データ提供：米国国立医学図書館（NLM）

Oral Acyclovir for HSV Iridocyclitis: A Potential Boon

Herpes simplex virus (HSV) can cause a range of ocular infections, including iridocyclitis, an inflammation of the iris and ciliary body. This study investigates the potential benefit of adding oral acyclovir to a standard treatment regimen of topical prednisolone phosphate and trifluridine for HSV iridocyclitis. While the trial was stopped prematurely due to slow recruitment, the results suggest a possible benefit of oral acyclovir in reducing treatment failure. This research provides valuable insights into the potential of oral acyclovir as an adjunct therapy for HSV iridocyclitis, warranting further investigation.

Oral Acyclovir: A Potential Game Changer for HSV Iridocyclitis

The study's findings, while preliminary, suggest that oral acyclovir could be a valuable addition to the treatment of HSV iridocyclitis. The observed trend towards reduced treatment failure warrants further investigation, as this could significantly improve the management of this challenging ocular infection.

A New Frontier in HSV Iridocyclitis Treatment: More Options, More Hope

Imagine a world where HSV iridocyclitis is effectively treated, preventing vision loss and minimizing discomfort. This research brings us closer to that reality, offering a new approach to managing this ocular infection. The potential of oral acyclovir as an adjunct therapy is promising, paving the way for more effective and comprehensive treatment options for patients suffering from HSV iridocyclitis.

Dr.Camel's Conclusion

HSV iridocyclitis can be like a desert mirage, distorting vision and causing discomfort. Oral acyclovir, with its potential to reduce treatment failure, acts like a guiding beacon, helping us navigate the treacherous path of HSV infection. This research, while preliminary, provides a glimmer of hope for a brighter future, where we can conquer this challenging infection and restore clear vision.

Date :
  1. Date Completed 1996-10-03
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

8790090

DOI: Digital Object Identifier

10.1001/archopht.1996.01100140267002

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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