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Pindolol and methylphenidate in children with attention-deficit hyperactivity disorder. Clinical efficacy and side-effects.
Author: BuitelaarJ K, KuiperM, Swaab-BarneveldH, van der GaagR J
Original Abstract of the Article :
The purpose of this study was to examine the efficacy and side-effects of pindolol, a beta-blocker, in children with attention-deficit hyperactivity disorder (ADHD). Fifty-two ADHD children, 7-13 years old, participated in a prospective double-blind placebo-controlled comparison of pindolol and meth...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1469-7610.1996.tb01445.x
データ提供:米国国立医学図書館(NLM)
Pindolol: A New Hope for Treating ADHD?
Attention-Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder affecting millions worldwide. This study explored the effectiveness and side effects of pindolol, a beta-blocker, in treating ADHD in children. The researchers conducted a double-blind, placebo-controlled comparison of pindolol with methylphenidate (MPH), a commonly prescribed medication for ADHD.
Pindolol: A Promising Alternative with Cautionary Side Effects
The study revealed that pindolol was modestly effective in reducing hyperactivity and conduct problems, comparable to MPH. However, pindolol was associated with a higher incidence of side effects such as paraesthesias, nightmares, and hallucinations, leading to safety concerns that limited its use.
A Balanced Approach to ADHD Treatment: A Multifaceted Desert
This study highlights the need for a balanced approach to ADHD treatment, taking into account both the potential benefits and risks of different medications. The desert of ADHD research is vast, and different medications offer unique pathways to navigate the complexities of this disorder. Understanding the specific needs and risk factors of individual patients is crucial for selecting the most appropriate treatment.
Dr.Camel's Conclusion
The search for effective treatments for ADHD is a journey through a complex and challenging desert. This study explores the potential of pindolol as a promising alternative to traditional medications. While pindolol offers potential benefits, its side effects warrant careful consideration. Finding the right treatment path for each individual requires a nuanced understanding of their specific needs and risk factors.
Date :
- Date Completed 1996-12-26
- Date Revised 2022-03-11
Further Info :
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