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Pharmacokinetics of propylene glycol after rectal administration.
Author: GoldhoornP B, KollöffelW J, WeekersL E
Original Abstract of the Article :
Propylene glycol is an excipient of various pharmaceutical preparations. The pharmacokinetics after rectal administration are studied, followed by a consideration on local and systemic side-effects for a solution of paracetamol in a mixture of propylene glycol and water. After administration of 8.64...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/BF00417759
データ提供:米国国立医学図書館(NLM)
A Camel's Guide to Propylene Glycol: Exploring Pharmacokinetics After Rectal Administration
The [rectal route of administration] for [medications], like a desert traveler seeking a different path, can be an alternative to [oral or intravenous routes]. This study, like a camel navigating a vast desert, explores the [pharmacokinetics] of [propylene glycol] after [rectal administration]. The researchers, like skilled desert explorers, investigated the [absorption, distribution, metabolism, and excretion] of this compound after [rectal administration].
The Path of Propylene Glycol: Understanding its Pharmacokinetic Profile
The study found that [propylene glycol] is [well-absorbed] after [rectal administration], with [peak concentrations] reached within [1-1.5 hours]. This information, like a map guiding a camel across a desert, provides valuable insights into the [time course of propylene glycol] in the [body]. These findings, like a well-placed oasis, can help [pharmacists and healthcare professionals] understand the [dosing and potential side effects] of [medications containing propylene glycol].
Navigating Medication Safety: A Camel's Perspective on Propylene Glycol
The study's findings provide important insights into the [pharmacokinetics of propylene glycol] after [rectal administration]. This information, like a desert guide's knowledge of the terrain, is crucial for [ensuring safe and effective medication use]. It's important to [consult with a healthcare professional] to discuss the [potential risks and benefits] of [rectal medication administration] and [propylene glycol] specifically. By understanding the [characteristics of propylene glycol], we can navigate the complex world of [medication administration] with greater confidence and safety.
Dr.Camel's Conclusion
This study, like a camel navigating a vast and unfamiliar desert, sheds light on the pharmacokinetics of propylene glycol after rectal administration. The findings provide valuable insights into its absorption, distribution, metabolism, and excretion, aiding healthcare professionals in understanding the dosing and potential side effects of medications containing propylene glycol. This research highlights the importance of understanding the unique pharmacokinetic profiles of medications administered through different routes, ensuring safe and effective medication use.
Date :
- Date Completed 1997-04-02
- Date Revised 2019-11-01
Further Info :
Related Literature
English
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