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A comparison of the antihypertensive effectiveness of a combination of moexipril or sustained-release verapamil with low-dose hydrochlorothiazide.

Author: ChrysantS G, StimpelM

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Both moexipril and verapamil SR produced an additive hypertensive effect when added to low-dose hydrochlorothiazide.
Paper Details　
Original Abstract of the Article :
The antihypertensive effectiveness of moexipril, a new angiotensin-converting enzyme (ACE) inhibitor, and sustained-release verapamil (verapamil SR) in combination with low-dose hydrochlorothiazide was investigated in patients with moderate to severe (Stages II and III) essential hypertension. Of 14...See full text at original site
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引用元：
https://doi.org/10.1002/j.1552-4604.1996.tb04238.x

データ提供：米国国立医学図書館（NLM）

Combining Antihypertensive Medications: A Synergistic Approach

High blood pressure, or hypertension, is a significant health concern, affecting millions globally. This research investigated the effectiveness of combining two antihypertensive medications, moexipril or sustained-release verapamil, with low-dose hydrochlorothiazide, in treating moderate to severe hypertension. The study found that both combinations effectively lowered blood pressure, highlighting the potential of this synergistic approach in managing hypertension.

Synergy in Antihypertensive Therapy

This study demonstrates the effectiveness of combining antihypertensive medications like moexipril or sustained-release verapamil with hydrochlorothiazide. This synergistic approach led to a significant reduction in blood pressure in patients with moderate to severe hypertension.

A Personalized Approach to Blood Pressure Management

Managing hypertension effectively requires a personalized approach. Consult with your doctor to determine the best treatment plan for your individual needs, considering factors like your medical history, lifestyle, and potential side effects of different medications.

Dr. Camel's Conclusion

Just as a camel needs to carefully choose its path through the desert to avoid obstacles, managing hypertension requires a thoughtful and personalized approach. This research highlights the effectiveness of combining antihypertensive medications to achieve optimal blood pressure control. Remember, working closely with your healthcare provider is essential for finding the right treatment path to a healthier and happier life.
Date :
  1. Date Completed 1997-02-19
  2. Date Revised 2019-08-26
Further Info :

Pubmed ID

8877673

DOI: Digital Object Identifier

10.1002/j.1552-4604.1996.tb04238.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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