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Comparison of four different treatment regimes in hirsutism related to polycystic ovary syndrome.

Author: GökmenO, GülekliB, IşikA Z, SenözS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

In a study of 141 women with polycystic ovary syndrome (PCOS) and excessive hair growth (hirsutism), four treatments were compared: low-dose birth control pills, cyproterone acetate, spironolactone, and ketoconazole. All treatments were effective in reducing hirsutism, with ketoconazole showing the most significant improvement (34.6% reduction in hair growth). While all treatments increased good cholesterol, the increase was smaller with ketoconazole compared to birth control pills and cyproterone acetate. Free testosterone levels decreased after treatment, with the largest decrease seen in the ketoconazole group. While ketoconazole appears promising for treating hirsutism related to PCOS, further research on its effects on blood lipids is needed, as PCOS involves more than just excessive hair growth.
Paper Details　
Original Abstract of the Article :
Polycystic ovary syndrome is the most common endocrinological problem associated with hirsutism. The objective of this study was to compare four different treatment modalities for hirsutism related to this syndrome. Pelvic ultrasonography was performed on all patients who were referred to our Reprod...See full text at original site
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引用元：
https://doi.org/10.3109/09513599609012316

データ提供：米国国立医学図書館（NLM）

Battling Hirsutism: Finding the Right Treatment for Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) can be a challenging condition, often leading to unwanted hair growth, also known as hirsutism. This study investigates the effectiveness of four different treatment modalities for hirsutism related to PCOS, comparing their impact on hair growth, hormonal levels, and lipid profiles. It's like a quest through a diverse desert landscape, searching for the most effective route to alleviate this condition.

Ketoconazole Emerges as a Strong Contender for Hirsutism Treatment

The study found that ketoconazole, an antifungal medication, was the most effective in reducing hirsutism compared to other treatment options like combined oral contraceptives, cyproterone acetate, and spironolactone. It's like discovering a hidden oasis that provides the best solution for tackling this condition. While ketoconazole demonstrated promising results, the study acknowledges the need for further investigation into its impact on lipoprotein profile, as this aspect requires additional research and understanding. This is like exploring a new territory and discovering the need for further exploration and mapping to fully understand its implications.

Managing PCOS: A Multifaceted Approach

This research underscores the importance of a personalized approach to treating PCOS and its associated symptoms. It highlights the need for a tailored strategy that considers the individual's specific needs and circumstances. This involves working closely with healthcare professionals to develop a comprehensive plan that addresses all aspects of the condition. Just as a camel adapts its behavior to the desert environment, we can learn to manage PCOS by embracing a personalized approach that considers our unique needs and preferences.

Dr.Camel's Conclusion

This research offers valuable insights into the treatment of hirsutism related to PCOS, highlighting the potential benefits of ketoconazole. However, it also emphasizes the need for further investigation into the long-term effects of this medication. As a camel adapts to the desert environment, we too must approach healthcare with a spirit of exploration and adaptation, seeking the best possible solutions for our well-being.

Date :
  1. Date Completed 1997-02-25
  2. Date Revised 2019-11-01
Further Info :

Pubmed ID

8908525

DOI: Digital Object Identifier

10.3109/09513599609012316

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・Effective treatment of polycystic ovary syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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