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Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination.

Author: KestinI G, MontgomeryJ E, SneydJ R, SutherlandC J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A combination of diclofenac and paracetamol reduced morphine consumption compared with paracetamol alone in patients undergoing elective abdominal gynecological surgery. There was no difference in the incidence of morphine-related side effects between the groups.
Paper Details　
Original Abstract of the Article :
Paracetamol and diclofenac have different mechanisms of action, and the combination may be more effective than each drug used alone in treating postoperative pain. In a double-blind, controlled design, we studied 60 patients undergoing elective abdominal gynaecological surgery, who received supposit...See full text at original site
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引用元：
https://doi.org/10.1093/bja/77.4.445

データ提供：米国国立医学図書館（NLM）

A Pain Relief Combination: Paracetamol and Diclofenac for Postoperative Pain

Imagine trekking through a desert, battling the scorching heat and aching joints. That's what it's like for patients recovering from surgery! This study, published in The British Journal of Anaesthesia, explores a novel approach to postoperative pain management that combines paracetamol and diclofenac.

The study compared the effectiveness of three different treatments: paracetamol alone, diclofenac alone, and a combination of paracetamol and diclofenac. The researchers found that the combination therapy significantly reduced the amount of morphine needed to manage pain compared to paracetamol alone. The incidence of morphine-related side effects was similar across all groups.

Combining Medications for Better Pain Relief

The results of this study suggest that combining paracetamol and diclofenac may be a more effective approach to managing postoperative pain than using either medication alone. The combination therapy allows for a reduction in morphine use, which can potentially decrease the risk of side effects.

A More Effective Approach to Postoperative Pain Management

This study offers hope for patients recovering from surgery, providing a potentially more effective and safer approach to managing postoperative pain. The combination of paracetamol and diclofenac may help reduce the need for morphine, leading to fewer side effects and faster recovery. It's essential to discuss your treatment options with your doctor to determine the best course of action for your specific needs.

Dr.Camel's Conclusion

This study demonstrates the effectiveness of combining paracetamol and diclofenac for managing postoperative pain, reducing the need for morphine and potentially minimizing side effects. This approach may offer a more effective and safer option for patients recovering from surgery.

Date :
  1. Date Completed 1996-12-30
  2. Date Revised 2019-05-15
Further Info :

Pubmed ID

8942325

DOI: Digital Object Identifier

10.1093/bja/77.4.445

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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