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A comparative study of the effects of timolol and latanoprost on blood flow velocity of the retrobulbar vessels.

Author: BuckleyA R, DranceS M, NicolelaM T, WalmanB E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Topical timolol and latanoprost significantly reduced intraocular pressure in ocular hypertensive and glaucoma patients without causing significant hemodynamic changes in the retrobulbar vessels.
Paper Details　
Original Abstract of the Article :
PURPOSE: To examine the effects of topical timolol and latanoprost on retrobulbar vessel blood velocity in patients with glaucoma or ocular hypertension. METHODS: Nine patients with primary open-angle glaucoma and six patients with ocular hypertension were enrolled for this study. All patients were...See full text at original site
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引用元：
https://doi.org/10.1016/s0002-9394(14)70374-5

データ提供：米国国立医学図書館（NLM）

Timolol and Latanoprost: A Tale of Two Glaucoma Medications

Glaucoma, a condition characterized by increased intraocular pressure, can lead to irreversible vision loss. This study explores the effects of two common glaucoma medications, timolol and latanoprost, on blood flow velocity in the retrobulbar vessels, the blood vessels behind the eye. Researchers sought to understand whether these medications, while effective in reducing intraocular pressure, might have any unintended consequences on blood flow in this critical area.

Glaucoma Medications: A Balancing Act

The study found that both timolol and latanoprost effectively reduced intraocular pressure without causing significant changes in blood flow velocity in the retrobulbar vessels. This finding is reassuring, suggesting that these medications can be used to manage glaucoma without compromising blood flow to the eye. However, timolol did cause a slight reduction in end diastolic velocity in the ophthalmic artery, suggesting a potential impact on blood flow dynamics. Further research is needed to fully understand the long-term effects of these medications on blood flow in the retrobulbar vessels.

Navigating the Desert of Glaucoma: A Multifaceted Approach

Managing glaucoma is like navigating a vast desert, where each step requires careful consideration. This study provides valuable insights into the potential effects of timolol and latanoprost on blood flow in the retrobulbar vessels. While these medications can be effective in reducing intraocular pressure, they may have subtle effects on blood flow dynamics. This underscores the importance of ongoing monitoring and personalized treatment plans, tailored to the unique needs of each patient.

Dr.Camel's Conclusion

This study offers a glimpse into the subtle interplay between glaucoma medications and blood flow dynamics. While the medications show promise in managing intraocular pressure, their potential impact on blood flow warrants further investigation. Like navigating a desert, managing glaucoma requires a multifaceted approach, balancing the benefits of treatment with the need for careful monitoring and personalized care.

Date :
  1. Date Completed 1996-12-31
  2. Date Revised 2019-06-27
Further Info :

Pubmed ID

8956632

DOI: Digital Object Identifier

10.1016/s0002-9394(14)70374-5

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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