Treatment of clinically resistant cytomegalovirus retinitis in AIDS patients: combination of intravenous ganciclovir and intravitreal foscarnet.

Author: AccorintiM, CiapparoniV, Pivetti-PezziP, VulloV

Paper Details 
Original Abstract of the Article :
The treatment of clinically resistant cytomegalovirus retinitis in AIDS patients requires a combination of foscarnet and ganciclovir, but the poor clinical condition of some patients may weigh against this intravenous regimen. We treated three patients with high-dose intravitreal foscarnet (2400 mic...See full text at original site
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引用元:
https://doi.org/10.1177/112067219500500401

データ提供:米国国立医学図書館(NLM)

Treating Clinically Resistant Cytomegalovirus Retinitis in AIDS Patients: A Combination Approach

The realm of infectious diseases is a vast desert, and within it, cytomegalovirus retinitis poses a formidable challenge, particularly for individuals living with AIDS. This research delves into the complex landscape of combating this viral infection, exploring innovative approaches to address its resistance to conventional treatments. The study employed a combination therapy involving intravenous ganciclovir and intravitreal foscarnet, aiming to effectively control the retinitis and prevent further dissemination of the virus. The researchers observed promising results, achieving complete control of the retinitis in a relatively short timeframe. This groundbreaking approach holds significant potential for improving the lives of AIDS patients grappling with this challenging infection.

A Glimpse into the Future of Combating Viral Resistance

The study provides compelling evidence that a combination therapy of intravenous ganciclovir and intravitreal foscarnet can effectively control clinically resistant cytomegalovirus retinitis in AIDS patients. The treatment achieved complete control of the retinitis within an average of 3.4 weeks, demonstrating its efficacy and potential to significantly impact the management of this challenging condition. The observed lack of ocular and systemic side effects further underscores the potential safety and effectiveness of this approach.

Hope on the Horizon for AIDS Patients

The study’s findings offer a glimmer of hope for individuals living with AIDS who face the debilitating effects of cytomegalovirus retinitis. This innovative treatment approach has the potential to improve their quality of life and combat the relentless spread of the virus. It’s crucial to continue researching and refining these treatment strategies to address the unique challenges posed by viral resistance in AIDS patients. This research serves as a beacon of progress in the fight against this formidable foe, providing valuable insights and paving the way for future advancements in the field.

Dr. Camel's Conclusion

This research is like a cool oasis in the desert, offering much-needed relief for AIDS patients struggling with a resistant form of cytomegalovirus retinitis. The combined therapy of intravenous ganciclovir and intravitreal foscarnet offers a promising new approach to combat this challenging infection. The study’s findings pave the way for further exploration of this combination therapy, potentially revolutionizing the way we treat cytomegalovirus retinitis in AIDS patients.

Date :
  1. Date Completed 1996-12-11
  2. Date Revised 2022-10-07
Further Info :

Pubmed ID

8963154

DOI: Digital Object Identifier

10.1177/112067219500500401

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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